Shi You Ding

TL;DR: Here, the natural resistance of plant cell walls to microbial and enzymatic deconstruction is considered, collectively known as “biomass recalcitrance,” which is largely responsible for the high cost of lignocellulose conversion.

TL;DR: It is demonstrated that the small, noncomplexed fungal cellulases deconstruct cell walls using mechanisms that differ considerably from those of the larger, multienzyme complexes (cellulosomes), and high-resolution measurement of the microfibrillar architecture of cell walls suggests that digestion is primarily facilitated by enabling enzyme access to the hydrophobic cellulose face.

TL;DR: Isolation of high-value lignocellulose components (lignin, acetic acid, and hemicellulose) would greatly increase potential revenues of a ligne cellulose biorefinery.

TL;DR: A new molecular model consisting of a 36-glucan-chain elementary fibril, in which the 36- glucan chains form both crystalline and subcrystalline structures is proposed based on recently reported experimental evidence from plant cell wall biosynthesis.

TL;DR: This review highlights literature on the impact of key substrate and enzyme features that influence performance to better understand fundamental strategies to advance enzymatic hydrolysis of cellulosic biomass for biological conversion to fuels and chemicals.