S
Shinji Kasai
Researcher at National Institutes of Health
Publications - 109
Citations - 3807
Shinji Kasai is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Gene & Knockdown resistance. The author has an hindex of 33, co-authored 92 publications receiving 3209 citations. Previous affiliations of Shinji Kasai include University of Tsukuba & Cornell University.
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Journal ArticleDOI
Correlation of pyrethroid structure and resistance level in Culex quinquefasciatus Say from Saudi Arabia
TL;DR: JPal-per-per系統は実験に用いた13種の抵抗性レベルを調べた; JPal- per-per £5.6～4160倍という開きが認められた.
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High-throughput genotyping of a full voltage-gated sodium channel gene via genomic DNA using target capture sequencing and analytical pipeline MoNaS to discover novel insecticide resistance mutations.
Kentaro Itokawa,Tsuyoshi Sekizuka,Yoshihide Maekawa,Koji Yatsu,Osamu Komagata,Masaaki Sugiura,Tomonori Sasaki,Takashi Tomita,Makoto Kuroda,Kyoko Sawabe,Shinji Kasai +10 more
TL;DR: An automated pipeline is developed—MoNaS (Mosquito Na+ channel mutation Search)—which calls amino acid substitutions in the VGSC from NGS reads and compares those to known resistance mutations and should facilitate the discovery of novel amino acid variants conferring insecticide resistance on VGSC.
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Two novel house fly Vssc mutations, D600N and T929I, give rise to new insecticide resistance alleles.
TL;DR: This work isolated strains having the unique Vssc alleles, but being otherwise congenic to the susceptible strain, aabys, and revealed that addition of T929I to the kdr mutation increased resistance to all pyrethroids (except etofenprox), and enhanced resistance by ~1000-fold to acrinathrin and flumethrin.
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Alternative splicing and developmental regulation of glutathione transferases in Culex quinquefasciatus Say.
TL;DR: In this article, an alternatively spliced gene that encodes delta glutathione transferases (GSTs) (CqGSTdelta1) in Culex quinquefasciatus was identified and characterized.
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Two cases of eruptive pseudoangiomatosis induced by mosquito bites.
TL;DR: It is demonstrated that eruptive pseudoangiomatosis was the response manifested in individuals who normally did not demonstrate any immediate or delayed reaction to insect bites; and the typical eruption was elicited by C. pipiens mosquito bites.