S
Shou-Wei Ding
Researcher at University of California, Riverside
Publications - 88
Citations - 17032
Shou-Wei Ding is an academic researcher from University of California, Riverside. The author has contributed to research in topics: RNA & RNA interference. The author has an hindex of 48, co-authored 81 publications receiving 14905 citations. Previous affiliations of Shou-Wei Ding include National University of Singapore & University of Adelaide.
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Antiviral Immunity Directed by Small RNAs
Shou-Wei Ding,Olivier Voinnet +1 more
TL;DR: The proteins required for viRNA production as well as several key downstream components of the antiviral immunity pathway have been identified in plants, flies, and worms, illuminating an ongoing molecular arms race that likely impacts the evolution of both viral and host genomes.
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Viral pathogenicity determinants are suppressors of transgene silencing in Nicotiana benthamiana.
TL;DR: By expressing PVY and CMV‐encoded proteins in a PVX vector, it is shown that the viral suppressors of gene silencing are the HCPro of PVy and the 2b protein of CMV.
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Skewer: a fast and accurate adapter trimmer for next-generation sequencing paired-end reads.
TL;DR: A novel algorithm, the bit-masked k-difference matching algorithm, which has O(kn) expected time with O(m) space, where k is the maximum number of differences allowed, n is the read length, and m is the adapter length is devised, which achieves as yet unmatched accuracies for adapter trimming with low time bound.
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Induction and Suppression of RNA Silencing by an Animal Virus
TL;DR: It is shown that flock house virus (FHV) is both an initiator and a target of RNA silencing in Drosophila host cells and that FHV infection requires suppression of RNAsilencing by an FHv-encoded protein, B2.
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RNA virus interference via CRISPR/Cas13a system in plants.
Rashid Aman,Zahir Ali,Haroon Butt,Ahmed Mahas,Fatimah R. Aljedaani,Muhammad Zhuhaib Khan,Shou-Wei Ding,Magdy M. Mahfouz +7 more
TL;DR: The data indicate that CRISPR/Cas13a can be used for engineering interference againstRNA viruses, providing a potential novel mechanism for RNA-guided immunity against RNA viruses and for other RNA manipulations in plants.