Shuangge Ma

TL;DR: In this article, the authors characterized the mutational landscape of melanoma, the form of skin cancer with the highest mortality rate, by sequencing the exomes of 147 melanomas and found that sun-exposed melanomas had markedly more ultraviolet-like C>T somatic mutations compared to sun-shielded acral, mucosal and uveal melanomas.

TL;DR: The adaptive Lasso has the oracle property even when the number of covariates is much larger than the sample size, and under a partial orthogonality condition in which the covariates with zero coefficients are weakly correlated with the covariate with nonzero coefficients, marginal regression can be used to obtain the initial estimator.

TL;DR: Simulation studies and analyses of multiple pancreatic and liver cancer experiments demonstrate the superior performance of the Meta Threshold Gradient Descent Regularization approach for gene selection in the meta analysis of cancer microarray data.

TL;DR: In this article, a high-throughput autoantibody discovery technique known as rapid extracellular antigen profiling was used to screen a cohort of 194 individuals infected with SARS-CoV-2, comprising 172 patients with COVID-19 and 22 health care workers with mild disease or asymptomatic infection, for auto-antibodies against 2,770 proteins (members of the exoproteome).

TL;DR: In this paper, the authors studied the asymptotic properties of bridge estimators in sparse, high-dimensional, linear regression models when the number of covariates may increase to infinity with the sample size.