Anne E. Watkins

TL;DR: In this article, a high-throughput autoantibody discovery technique known as rapid extracellular antigen profiling was used to screen a cohort of 194 individuals infected with SARS-CoV-2, comprising 172 patients with COVID-19 and 22 health care workers with mild disease or asymptomatic infection, for auto-antibodies against 2,770 proteins (members of the exoproteome).

TL;DR: Excess deaths provide an estimate of the full COVID-19 burden and indicate that official tallies likely undercount deaths due to the virus.

TL;DR: It is established that these autoantibodies perturb immune function and impair virological control by inhibiting immunoreceptor signaling and by altering peripheral immune cell composition, and found that murine surrogates of these autoantsibodies exacerbate disease severity in a mouse model of SARS-CoV-2 infection.

TL;DR: SalivaDirect as discussed by the authors is a saliva-based diagnostic test for SARS-CoV-2 screening and has been shown to be a valid alternative to swabs for large-scale testing.

TL;DR: In this paper, the authors designed and validated an open-source PCR assay to detect SARS-CoV-2 VOC using ORF1a Δ3675-3677 as the primary target and spike Δ69-70 to differentiate.