S
Shuji Yamamoto
Researcher at Osaka University
Publications - 48
Citations - 1997
Shuji Yamamoto is an academic researcher from Osaka University. The author has contributed to research in topics: Corneal dystrophy & Gene mutation. The author has an hindex of 24, co-authored 47 publications receiving 1907 citations.
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Journal ArticleDOI
Macular corneal dystrophy type I and type II are caused by distinct mutations in a new sulphotransferase gene.
Tomoya O. Akama,Kohji Nishida,Kohji Nishida,Jun Nakayama,Jun Nakayama,Hitoshi Watanabe,Kouichi Ozaki,Takahiro Nakamura,Atsuyoshi Dota,Satoshi Kawasaki,Yoshitsugu Inoue,Naoyuki Maeda,Shuji Yamamoto,Tsutomu Fujiwara,Eugene J.-M.A. Thonar,Yoshikazu Shimomura,Shigeru Kinoshita,Akira Tanigami,Michiko N. Fukuda +18 more
TL;DR: A new carbohydrate sulphotransferase gene (CHST6), encoding an enzyme designated corneal N-acetylglucosamine-6-sulphotranferase (C-GlcNAc6ST), is identified within the critical region of MCD type I, suggesting that mutations found in type II lead to loss of cornea-specific expression of CHST6.
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Ocular Surface Abnormalities in Aniridia
TL;DR: Findings suggest that, in the aniridic eye, conjunctival epithelium invades the cornea because of corneal epithelial stem cell deficiency.
Journal ArticleDOI
PAX6 Mutation as a Genetic Factor Common to Aniridia and Glucose Intolerance
Tetsuyuki Yasuda,Yoshitaka Kajimoto,Yoshio Fujitani,Hirotaka Watada,Shuji Yamamoto,Takao Watarai,Yutaka Umayahara,Munehide Matsuhisa,Shin-ichi Gorogawa,Yasuaki Kuwayama,Yasuo Tano,Yoshimitsu Yamasaki,Masatsugu Hori +12 more
TL;DR: The present observations suggest that heterozygous mutations in the PAX6 gene can induce eye anomaly and glucose intolerance in individuals harboring these mutations.
Journal ArticleDOI
A kerato-epithelin (betaig-h3) mutation in lattice corneal dystrophy type IIIA.
Shuji Yamamoto,Masaki Okada,Motokazu Tsujikawa,Yoshikazu Shimomura,Kohji Nishida,Yoshitsugu Inoue,Hitoshi Watanabe,Naoyuki Maeda,Hiroki Kurahashi,Shigeru Kinoshita,Yusuke Nakamura,Yasuo Tano +11 more
Journal ArticleDOI
Transforming growth factor-beta 1, -beta 2 and -beta 3 mRNA expression in human cornea.
TL;DR: It is demonstrated that both protein and mRNA of TGF-beta 2-LAP are present in human corneal epithelium, indicating that TGF -beta 2 may play a crucial role in cornean epithelial cell layers.