S
Sinead Delany
Researcher at University of the Witwatersrand
Publications - 18
Citations - 1646
Sinead Delany is an academic researcher from University of the Witwatersrand. The author has contributed to research in topics: Acquired immunodeficiency syndrome (AIDS) & Viral load. The author has an hindex of 13, co-authored 18 publications receiving 1537 citations.
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Journal ArticleDOI
Acyclovir and transmission of HIV-1 from persons infected with HIV-1 and HSV-2.
Connie Celum,Anna Wald,Anna Wald,J.R. Lingappa,Amalia Magaret,Amalia Magaret,Richard S. Wang,Nelly Mugo,Nelly Mugo,Andrew Mujugira,Jared M. Baeten,James I. Mullins,James P. Hughes,Elizabeth A. Bukusi,Elizabeth A. Bukusi,Elizabeth A. Bukusi,Craig R. Cohen,Elly Katabira,Allan R. Ronald,James Kiarie,Carey Farquhar,Grace John Stewart,Joseph Makhema,Myron Essex,Edwin Were,Kenneth H. Fife,G de Bruyn,Glenda Gray,James McIntyre,Rachel Manongi,Saidi Kapiga,David Coetzee,Susan Allen,Mubiana Inambao,Kayitesi Kayitenkore,Etienne Karita,William Kanweka,Sinead Delany,Helen Rees,Bellington Vwalika,Wendy S. Stevens,Campbell,Katherine K. Thomas,Robert W. Coombs,Rhoda Ashley Morrow,William L. H. Whittington,M J McElrath,M J McElrath,Linda E Barnes,Renee Ridzon,Lawrence Corey,Lawrence Corey +51 more
TL;DR: Daily acyclovir therapy did not reduce the risk of transmission of HIV-1, despite a reduction in plasma HIV- 1 RNA of 0.25 log(10) copies per milliliter and a 73% reduction in the occurrence of genital ulcers due to HSV-2.
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Bacterial vaginosis associated with increased risk of female-to-male HIV-1 transmission: a prospective cohort analysis among African couples.
Craig R. Cohen,Jairam R. Lingappa,Jared M. Baeten,Musa Otieno Ngayo,Carol A. Spiegel,Ting Hong,Deborah Donnell,Connie Celum,Saidi Kapiga,Sinead Delany,Elizabeth A. Bukusi +10 more
TL;DR: In a prospective study, Craig Cohen and colleagues investigate the association between bacterial vaginosis and the risk of female-to-male HIV-1 transmission.
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Optimal uses of antiretrovirals for prevention in HIV-1 serodiscordant heterosexual couples in South Africa: a modelling study.
Timothy B. Hallett,Jared M. Baeten,Renee Heffron,Ruanne V. Barnabas,Guy de Bruyn,Ide Cremin,Sinead Delany,Geoffrey P. Garnett,Glenda Gray,Leigh F. Johnson,James McIntyre,Helen Rees,Connie Celum +12 more
TL;DR: A mathematical model is constructed to examine the impact and cost-effectiveness of different strategies, including earlier initiation of ART and/or PrEP, for HIV-1 prevention for serodiscordant couples.
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Daily aciclovir for HIV-1 disease progression in people dually infected with HIV-1 and herpes simplex virus type 2: a randomised placebo-controlled trial.
Jairam R. Lingappa,Jared Baeten,Anna Wald,James P. Hughes,Katherine K Thomas,Andrew Mujugira,Nelly Mugo,Elizabeth A. Bukusi,Elizabeth A. Bukusi,Craig R. Cohen,Elly Katabira,Allan R. Ronald,James Kiarie,Carey Farquhar,Grace John Stewart,Joseph Makhema,Myron Essex,Edwin Were,Kenneth H. Fife,Guy de Bruyn,Glenda Gray,James McIntyre,Rachel Manongi,Saidi Kapiga,David Coetzee,Susan Allen,Mubiana Inambao,Kayitesi Kayitenkore,Etienne Karita,William Kanweka,Sinead Delany,Helen Rees,Bellington Vwalika,Amalia Magaret,Amalia Magaret,Richard S. Wang,Lara Kidoguchi,Linda E Barnes,Renee Ridzon,Lawrence Corey,Lawrence Corey,Lawrence Corey,Connie Celum +42 more
TL;DR: The role of suppression of herpes simplex virus type 2 in reduction of HIV-1 disease progression before initiation of antiretroviral therapy warrants consideration.
Journal ArticleDOI
Injectable progestin contraceptive use and risk of HIV infection in a South African family planning cohort.
Immo Kleinschmidt,Helen Rees,Sinead Delany,Dawn K. Smith,Natalya Dinat,Busi Nkala,James McIntyre +6 more
TL;DR: There is no evidence of an association between HIV infection and injectable contraceptives among sexually active women using depot medroxyprogesterone acetate or noresthisterone enanthate injections for contraception than among women using nonhormonal or no contraception.