Kayitesi Kayitenkore

TL;DR: Since most heterosexual HIV transmission for both men and women in urban Zambia and Rwanda takes place within marriage or cohabitation, voluntary counselling and testing for couples should be promoted, as should other evidence-based interventions that target heterosexual couples.

TL;DR: Daily acyclovir therapy did not reduce the risk of transmission of HIV-1, despite a reduction in plasma HIV- 1 RNA of 0.25 log(10) copies per milliliter and a 73% reduction in the occurrence of genital ulcers due to HSV-2.

TL;DR: The distribution of HIV-1 subtypes and recombinants changed over time in countries, regions, and globally as well as at a global level during 2005-15, where subtype B increased, subtypes A and D were stable, and subtypes C and G and CRF02_AG decreased.

TL;DR: Establishing clinical laboratory reference intervals for 25 hematology, immunology and biochemistry values among healthy African adults typical of those who might join a clinical trial provides ranges that will inform inclusion criteria and evaluation of adverse events for studies in these regions of Africa.

TL;DR: The role of suppression of herpes simplex virus type 2 in reduction of HIV-1 disease progression before initiation of antiretroviral therapy warrants consideration.