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Soichiro Miura

Researcher at International University of Health and Welfare

Publications -  412
Citations -  12029

Soichiro Miura is an academic researcher from International University of Health and Welfare. The author has contributed to research in topics: Intestinal mucosa & Colitis. The author has an hindex of 52, co-authored 409 publications receiving 10760 citations. Previous affiliations of Soichiro Miura include National Defense Medical College & Keio University.

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Ameliorating effects of compounds derived from Salvia miltiorrhiza root extract on microcirculatory disturbance and target organ injury by ischemia and reperfusion.

TL;DR: The water-soluble and lipophilic compounds of SMRE appear to improve the I/R-induced vascular damage multifactorially and synergically and provide a new perspective on remedy with multiple drugs.
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Increased expression of an inducible isoform of nitric oxide synthase and the formation of peroxynitrite in colonic mucosa of patients with active ulcerative colitis

TL;DR: Nitric oxide and peroxynitrite formation may play an important role in causing irreversible cellular injury to the colonic mucosa in patients with active ulcerative colitis.
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Free cholesterol accumulation in hepatic stellate cells: mechanism of liver fibrosis aggravation in nonalcoholic steatohepatitis in mice.

TL;DR: Cholesterol intake accelerated liver fibrosis in both the mouse models without affecting the degree of hepatocellular injury or Kupffer cell activation and the characteristic mechanisms of FC accumulation in HSCs are potential targets to treat liver Fibrosis in liver diseases including NASH.
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Oxidative stress‐mediated apoptosis of hepatocytes exposed to acute ethanol intoxication

TL;DR: It is suggested that active oxidants produced during ethanol metabolism mediate fragmentation of DNA in hepatocytes, and that intracellular antioxidants such as glutathione play a critical role in the cytoprotective mechanisms of hepatocyte against lethal cell death, ie, apoptosis, induced by ethanol.