Stephen E. Hamby

TL;DR: C. sakazakii is unique in the Cronobacter genus in encoding genes enabling the utilization of exogenous sialic acid which may have clinical significance, and also suggested various degrees of divergence.

TL;DR: It is speculated that recruitment of an alternative stop codon at greater distance from the mutated stop codons may trigger nonstop mRNA decay, thereby decreasing the amount of protein product and yielding a readily discernible clinical phenotype.

TL;DR: The use of Expectation Maximization clustering was used to categorise 98 strains of Cronobacter as pathogenic or non-pathogenic based on biochemical test results from standard diagnostic test kits, demonstrating a computational approach allowing existing diagnostic kits to be used to identify pathogenic strains ofronobacter.

TL;DR: 109 cutaneous neurofibromas, excised from 46 unrelated NF1 patients, are screened for somatic NF1 mutations and no association was noted between the type of germline and somaticNF1 lesion within the same individual.

TL;DR: A comparison of somatic, germline, shared and somatic recurrent mutational spectra for 17 human tumor suppressor genes concluded that ∼50% of these somatic missense mutations possess features consistent with their being either shared or recurrent, suggesting that a disproportionate number of such lesions are likely to be drivers of tumorigenesis.