S
Stephen H. Bryant
Researcher at National Institutes of Health
Publications - 140
Citations - 34869
Stephen H. Bryant is an academic researcher from National Institutes of Health. The author has contributed to research in topics: PubChem & Conserved Domain Database. The author has an hindex of 57, co-authored 140 publications receiving 31359 citations. Previous affiliations of Stephen H. Bryant include Brookhaven National Laboratory.
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PubChem Substance and Compound databases
Sunghwan Kim,Paul A. Thiessen,Evan E Bolton,Jie Chen,Gang Fu,Asta Gindulyte,Lianyi Han,Jane He,Siqian He,Benjamin A. Shoemaker,Jiyao Wang,Bo Yu,Jian-Jian Zhang,Stephen H. Bryant +13 more
TL;DR: An overview of the PubChem Substance and Compound databases is provided, including data sources and contents, data organization, data submission using PubChem Upload, chemical structure standardization, web-based interfaces for textual and non-textual searches, and programmatic access.
Journal ArticleDOI
CDD: a Conserved Domain Database for the functional annotation of proteins
Aron Marchler-Bauer,Shennan Lu,John B. Anderson,Farideh Chitsaz,Myra K. Derbyshire,Carol DeWeese-Scott,Jessica H. Fong,Lewis Y. Geer,Renata C. Geer,Noreen R. Gonzales,Marc Gwadz,David I. Hurwitz,John D. Jackson,Zhaoxi Ke,Christopher J. Lanczycki,Fu-Ping Lu,Gabriele H. Marchler,Mikhail Mullokandov,Marina V. Omelchenko,Cynthia L. Robertson,James S. Song,Narmada Thanki,Roxanne A. Yamashita,Dachuan Zhang,Naigong Zhang,Chanjuan Zheng,Stephen H. Bryant +26 more
TL;DR: NCBI’s Conserved Domain Database (CDD) is a resource for the annotation of protein sequences with the location of conserved domain footprints, and functional sites inferred from these footprints.
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CDD: NCBI's conserved domain database
Aron Marchler-Bauer,Myra K. Derbyshire,Noreen R. Gonzales,Shennan Lu,Farideh Chitsaz,Lewis Y. Geer,Renata C. Geer,Jane He,Marc Gwadz,David I. Hurwitz,Christopher J. Lanczycki,Fu Lu,Gabriele H. Marchler,James S. Song,Narmada Thanki,Zhouxi Wang,Roxanne A. Yamashita,Dachuan Zhang,Chanjuan Zheng,Stephen H. Bryant +19 more
TL;DR: NCBI's CDD, the Conserved Domain Database, enters its 15th year as a public resource for the annotation of proteins with the location of conserved domain footprints and aims at increasing coverage and providing finer-grained classifications of common protein domains.
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CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.
Aron Marchler-Bauer,Yu Bo,Lianyi Han,Jane He,Christopher J. Lanczycki,Shennan Lu,Farideh Chitsaz,Myra K. Derbyshire,Renata C. Geer,Noreen R. Gonzales,Marc Gwadz,David I. Hurwitz,Fu Lu,Gabriele H. Marchler,James S. Song,Narmada Thanki,Zhouxi Wang,Roxanne A. Yamashita,Dachuan Zhang,Chanjuan Zheng,Lewis Y. Geer,Stephen H. Bryant +21 more
TL;DR: NCBI's Conserved Domain Database (CDD) aims at annotating biomolecular sequences with the location of evolutionarily conserved protein domain footprints, and functional sites inferred from such footprints.
Journal ArticleDOI
CD-Search: protein domain annotations on the fly
TL;DR: The Conserved Domain Search service (CD-Search), a web-based tool for the detection of structural and functional domains in protein sequences, uses BLAST(R) heuristics to provide a fast, interactive service, and searches a comprehensive collection of domain models.