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Steve Hindmarsh
Researcher at Francis Crick Institute
Publications - 13
Citations - 735
Steve Hindmarsh is an academic researcher from Francis Crick Institute. The author has contributed to research in topics: Medicine & Segmentation. The author has an hindex of 7, co-authored 11 publications receiving 257 citations.
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Journal ArticleDOI
Neutralising antibody activity against SARS-CoV-2 VOCs B.1.617.2 and B.1.351 by BNT162b2 vaccination.
Emma C Wall,Emma C Wall,Emma C Wall,Mary Wu,Ruth Harvey,Gavin Kelly,Scott Warchal,Chelsea Sawyer,Rodney S. Daniels,Philip Hobson,Emine Hatipoglu,Yenting Ngai,Saira Hussain,Jerome Nicod,Robert J. Goldstone,Karen Ambrose,Steve Hindmarsh,Rupert Beale,Rupert Beale,Rupert Beale,Andrew Riddell,Steve Gamblin,Michael Howell,George Kassiotis,George Kassiotis,Vincenzo Libri,Vincenzo Libri,Vincenzo Libri,Bryan Williams,Bryan Williams,Bryan Williams,Charles Swanton,Sonia Gandhi,Sonia Gandhi,David L.V. Bauer +34 more
Journal ArticleDOI
AZD1222-induced neutralising antibody activity against SARS-CoV-2 Delta VOC.
Emma C Wall,Emma C Wall,Emma C Wall,Mary Wu,Ruth Harvey,Gavin Kelly,Scott Warchal,Chelsea Sawyer,Rodney S. Daniels,Lorin Adams,Philip Hobson,Emine Hatipoglu,Yenting Ngai,Saira Hussain,Karen Ambrose,Steve Hindmarsh,Rupert Beale,Rupert Beale,Rupert Beale,Andrew Riddell,Steve Gamblin,Michael Howell,George Kassiotis,George Kassiotis,Vincenzo Libri,Vincenzo Libri,Vincenzo Libri,Bryan Williams,Bryan Williams,Bryan Williams,Charles Swanton,Charles Swanton,Sonia Gandhi,Sonia Gandhi,David L.V. Bauer +34 more
letters-and-commentsDOI
Three-dose vaccination elicits neutralising antibodies against omicron
Mary Y. Wu,Emma C. Wall,Edward J. Carr,Ruth Harvey,H C Townsley,Harriet V Mears,L. Garry Adams,Svend Kjaer,Gavin Kelly,Scott Warchal,Chelsea Sawyer,Caitlin Kavanagh,Christophe J. Queval,Yenting Ngai,Emine Hatipoglu,Karen Ambrose,Steve Hindmarsh,Rupert Beale,Steven J. Gamblin,Michael Howell,George Kassiotis,Vincenzo Libri,B. Williams,Sonia Gandhi,Charles Swanton,David L.V. Bauer +25 more
Journal ArticleDOI
Scalable and robust SARS-CoV-2 testing in an academic center.
Jim Aitken,Karen Ambrose,Sam Barrell,Rupert Beale,Rupert Beale,Ganka Bineva-Todd,Dhruva Biswas,Richard D. Byrne,Simon Caidan,Peter Cherepanov,Laura Churchward,Graham Clark,Margaret Crawford,Laura Cubitt,Vicky Dearing,Christopher Earl,Amelia Edwards,Chris Ekin,Efthymios Fidanis,Alessandra Gaiba,Steve Gamblin,Sonia Gandhi,Sonia Gandhi,Sonia Gandhi,Jacki Goldman,Robert J. Goldstone,Paul Grant,Maria Greco,Judith Heaney,Steve Hindmarsh,Catherine F Houlihan,Michael Howell,Mike Hubank,Mike Hubank,Deborah Hughes,Rachael Instrell,Deborah Jackson,Mariam Jamal-Hanjani,Mariam Jamal-Hanjani,Ming Jiang,Mark Johnson,Leigh Jones,Nnennaya Kanu,George Kassiotis,Stuart Kirk,Svend Kjaer,Andrew Levett,Lisa Levett,Marcel Levi,Wei-Ting Lu,James I. MacRae,John N. S. Matthews,Laura E. McCoy,Catherine Moore,David Allan Moore,David Allan Moore +55 more
TL;DR: A roadmap is provided to show how a European research institute can be repurposed in the midst of this crisis, in collaboration with partner hospitals and an established diagnostic laboratory, harnessing existing expertise in virus handling, robotics, molecular testing and informatics to derive a rapid, high-throughput diagnostic testing pipeline for detecting SARS-CoV-2 in individuals with suspected COVID-19.
Posted ContentDOI
Citizen science, cells and CNNs – deep learning for automatic segmentation of the nuclear envelope in electron microscopy data, trained with volunteer segmentations
Helen Spiers,Helen Spiers,Harry Songhurst,Harry Songhurst,Luke Nightingale,Joost de Folter,Roger Hutchings,Christopher J. Peddie,Anne Weston,Amy Strange,Steve Hindmarsh,Chris Lintott,Chris Lintott,Lucy M. Collinson,Martin L. Jones +14 more
TL;DR: A novel citizen science project, Etch a Cell, is developed to enable volunteers to manually segment the nuclear envelope of HeLa cells imaged with Serial Blockface SEM, and it is demonstrated that data produced exclusively by volunteers can be used to train a highly accurate machine learning algorithm for automatic segmentation of thenuclear envelope.