P
Paul Grant
Researcher at University College London Hospitals NHS Foundation Trust
Publications - 50
Citations - 3365
Paul Grant is an academic researcher from University College London Hospitals NHS Foundation Trust. The author has contributed to research in topics: Viral load & Virus. The author has an hindex of 23, co-authored 45 publications receiving 2233 citations. Previous affiliations of Paul Grant include National Health Service & University College Hospital.
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Genetic mechanisms of critical illness in Covid-19.
Erola Pairo-Castineira,Erola Pairo-Castineira,Sara Clohisey,Lucija Klaric,Andrew D. Bretherick,Konrad Rawlik,Dorota Pasko,Susan P. Walker,Nicholas J. Parkinson,Max Head Fourman,Clark D Russell,James J Furniss,Anne Richmond,E. Gountouna,Nicola Wrobel,David A Harrison,B. Wang,Yang Wu,A. Meynert,Fiona Griffiths,Wilna Oosthuyzen,Athanasios Kousathanas,Loukas Moutsianas,Z. Yang,R. Zhai,Canbin Zheng,Graeme R. Grimes,Rupert Beale,Jonathan E Millar,Barbara Shih,Seán Keating,Marie Zechner,Chris Haley,David J. Porteous,Caroline Hayward,Jian Yang,Julian C. Knight,Charlotte Summers,Manu Shankar-Hari,Manu Shankar-Hari,Paul Klenerman,Lance Turtle,Antonia Ho,S. C. Moore,Charles J. Hinds,P. Horby,Alistair Nichol,Alistair Nichol,Alistair Nichol,David M. Maslove,Lowell Ling,Daniel F. McAuley,Hugh Montgomery,Timothy S. Walsh,Alexandre C. Pereira,Alessandra Renieri,C. Ponting,J. Meikle,P. Finernan,E. Mcmaster,E. Mcmaster,Andy Law,J. K. Baillie,T. Paterson,T. Wackett,Robert C. Armstrong,Robert C. Armstrong,R. Clark,A. Coutts,L. Donnelly,Tamara Gilchrist,K. Hafezi,K. Hafezi,L. Macgillivray,L. Macgillivray,Alan MacLean,Sarah McCafferty,Kirstie Morrice,J. Weaver,C. Boz,C. Boz,A. Golightly,Minghong Ward,H. Mal,H. Szoor-McElhinney,Anthony Brown,Ross Hendry,A. Stenhouse,L. Cullum,D. Law,S. Law,R. Law,Maaike C. Swets,N. Day,F. Taneski,Emma L. Duncan,David Collier,S. Wood,A. Zak,C. Borra,M. Matharu,P. May,Z. Alldis,O. Mitchelmore,R. Bowles,A. Easthope,F. Bibi,I. Lancoma-Malcolm,J. Gurasashvili,J. Pheby,J. Shiel,M. Bolton,Minal Patel,M. Taylor,O. Zongo,P. Ebano,P. Harding,R. Astin-Chamberlain,Y. Choudhury,Anna Cox,D. Kallon,M. Burton,R. Hall,S. Blowes,Z. Prime,J. Biddle,O. Prysyazhna,T. Newman,C. Tierney,J. Kassam,Marlies Ostermann,S. Campos,A. Bociek,R. Lim,N. Grau,T. O. Jones,C. Whitton,M. Marotti,Gill Arbane,S. Bonner,K. Hugill,J. Reid,Ingeborg Welters,V. Waugh,Katherine Williams,D. Shaw,J. F. Roman,M. L. Martinez,Elizabeth M. Johnson,A. Waite,B. Johnston,D. Hamilton,S. Mulla,Mark J. W. McPhail,John A. S. Smith,L. Barclay,D. Hope,Corrienne McCulloch,L. McQuillan,S. Clark,J. Singleton,K. Priestley,N. Rea,M. Callaghan,R. Campbell,G. Andrew,L. Marshall,Stuart McKechnie,P. Hutton,A. Bashyal,N. Davidson,P. Polgarova,K. Stroud,N. Pathan,K. Elston,Sutapa Agrawal,Ceri Battle,L. Newey,Tim Rees,R. Harford,E. Brinkworth,Martin S. Williams,C. Murphy,I. M. S. White,M. Croft,N. Bandla,M. Gellamucho,J. Tomlinson,H. Turner,Michael Davies,A. Quinn,I. Hussain,Christopher C. Thompson,H. Parker,R. Bradley,R. Griffiths,J. Scriven,A. Nilsson,Matthew G.D. Bates,J. Dasgin,Janusz Gill,Alex Puxty,S. Cathcart,D. Salutous,L. Turner,K. Duffy,K. Puxty,Anna Maria Joseph,R. Herdman-Grant,R. Simms,A. Swain,A. Naranjo,R. Crowe,K. Sollesta,A. Loveridge,D. Baptista,E. Morino,M. Davey,D. Golden,J. Jones,J. Moreno Cuesta,A. Haldeos,D. Bakthavatsalam,Royce P Vincent,M. Elhassan,K. Xavier,Anand K. Ganesan,D. Purohit,M. Abdelrazik,J.M. Morgan,L. Akeroyd,S. Bano,T. Lawton,D. Warren,M. Bromley,K. Sellick,L. Gurr,B. Wilkinson,V. Nagarajan,P. Szedlak,Jason Cupitt,E. Stoddard,L. Benham,S. Preston,Shondipon Laha,N. Slawson,Z. Bradshaw,Jamie Brown,M. Caswell,S. Melling,P. Bamford,M. Faulkner,K. Cawley,H. Jeffrey,E. London,H. Sainsbury,I. Nagra,F. Nasir,C. Dunmore,R. L. Jones,A. Abraheem,M. Al-Moasseb,R. Girach,G. Padden,Josephine M. Egan,C. Brantwood,P. Alexander,J. Bradley-Potts,Susan Allen,Timothy Felton,S. Manna,S. Farnell-Ward,S. Leaver,J. Queiroz,E. Maccacari,D. Dawson,C. C. Delgado,R. P. Saluzzio,O. Ezeobu,L. Ding,C. Sicat,R. Kanu,G. Durrant,J. Texeira,Abby Harrison,T. Samakomva,H. Willis,B. Hopkins,L. Thrasyvoulou,M. Jackson,A. Zaki,C. Tibke,Suzanne Bennett,W. Woodyatt,A. Kent,E. Goodwin,C. Brandwood,Lee B. Smith,Kevin Rooney,Neil C. Thomson,N. Rodden,Ellen C Hughes,D. McGlynn,C. Clark,P. Clark,Laurent Abel,R. Sundaram,L. Gemmell,M. Brett,J. Hornsby,P. MacGoey,R. Price,B. Digby,P. O'Neil,P. McConnell,Paul Henderson,Seton J Henderson,M. Sim,S. Kennedy-Hay,C. McParland,L. Rooney,N. Baxter,D. Pogson,S. Rose,Z. Daly,L. Brimfield,Mandeep Phull,M. Hussain,T. Pogreban,L. Rosaroso,E. Salciute,L. Grauslyte,David Brealey,Eamon P. Raith,N. MacCallum,G. Bercades,I. Hass,D. Smyth,A. Reyes,G. Martir,I. D. Clement,K. Webster,C. Hays,A. Gulati,Luke Hodgson,M. Margarson,Refujia Gomez,Y. Baird,Y. Thirlwall,L. Folkes,A. Butler,E. Meadows,Shona C Moore,D. Raynard,Helen C. Fox,L. Riddles,K. King,S. Kimber,G. Hobden,Anne Marie McCarthy,V. Cannons,I. Balagosa,I. Chadbourn,A. Gardner,D. Horner,D. McLaughlanv,B. Charles,N. Proudfoot,T. Marsden,L. McMorrow,B. Blackledge,J. Pendlebury,Alison G. Harvey,E. Apetri,C. Basikolo,L. Catlow,R. Doonan,K. Knowles,S. Lee,David A. Lomas,C. Lyons,Joseph Perez,M. Poulaka,M. Slaughter,K. Slevin,V. Thomas,David W. Walker,Jennifer R. Harris,A. Drummond,R. Tully,J. Dearden,J. Philbin,S. Munt,C. Rishton,G. O'Connor,M. Mulcahy,E. Dobson,J. Cuttler,M. Edward,Jill M. Norris,K. Hanson,Alexis Poole,Alistair Rose,B. Sloan,S. Buckley,H. Brooke,E. Smithson,R. Charlesworth,R. Sandhu,M. Thirumaran,V. Wagstaff,J. C. Suarez,Agilan Kaliappan,M. Vertue,Andrew G. Nicholson,J. Riches,A. Solesbury,L. Kittridge,M. Forsey,G. Maloney,John B. Cole,R. Davies,H. Hill,E L Thomas,A. Williams,D. Duffin,B. Player,Jayachandran Radhakrishnan,Spencer B. Gibson,A. Lyle,F. McNeela,Brijesh V. Patel,M. Gummadi,G. Sloane,N. Dormand,S. Salmi,Z. Farzad,D. Cristiano,K. Liyanage,V. Thwaites,M. Varghese,M. Meredith,Gordon B. Mills,J. Willson,K. Harrington,B. Lenagh,K. Cawthron,S. Masuko,A. Raithatha,K. Bauchmuller,M. Wiles,N. Ahmad,Jack Barker,Y. Jackson,F. Kibutu,Sara W. Bird,G. Watson,Javier Martin,E. Bevan,C. W. Brown,D. Trodd,K. English,Graeme I. Bell,L. Wilcox,A. Katary,S. Gopal,V. Lake,N. Harris,S. Metherell,Elizabeth J. Radford,F. Moore,H. Bancroft,J. Daglish,M. Sangombe,M. Carmody,Johanna Rhodes,M. Bellamy,Atul Garg,A. Kuravi,E. Virgilio,P. Ranga,Javed Butler,L. Botfield,C. Dexter,Jason Fletcher,P. Shanmugasundaram,G. Hambrook,I. Burn,K. Manso,D. Thornton,J. Tebbutt,R. Penn,J. Hulme,Sabah N. A. Hussain,Z. Maqsood,Sarah B. Joseph,J. Colley,A. Hayes,C. Ahmed,R. Haq,S. Clamp,Rakesh Kumar,M. Purewal,B. Baines,M. Frise,N. Jacques,H. Coles,J. Caterson,S. G. Rai,M. Brunton,E. Tilney,L. Keating,Andrew Walden,David Antcliffe,Stephen J. Brett,Anthony C. Gordon,M. Templeton,Rocio Rojo,D. Banach,S. S. Arias,Z. Fernandez,P. Coghlan,D. Williams,Catherine Jardine,J. Bewley,Katie Sweet,L. Grimmer,Randall S. Johnson,Z. Garland,B. Gumbrill,C. Phillips,L. Ortiz-Ruiz de Gordoa,E. Peasgood,Ascanio Tridente,K. Shuker,S. Greer,C. Lynch,C. Pothecary,L. Roche,B. Deacon,K. Turner,Jai Rup Singh,G. S. Howe,P. Paul,Michael Gill,I. Wynter,V. Ratnam,S. Shelton,Jay Naisbitt,J. Melville,R. Baruah,Siouxzy Morrison,A. McGregor,V. Parris,M. Mpelembue,S. Srikaran,C. Dennis,A. Sukha,M. Verlander,K. Holding,K. Riches,C. Downes,C. Swan,A. Rostron,Ajit Roy,L. Woods,S. Cornell,F. Wakinshaw,Ben Creagh-Brown,H. Blackman,A. Salberg,E. N. Smith,S. Donlon,S. Mtuwa,N. Michalak-Glinska,S. Stone,C. Beazley,V. Pristopan,N. Nikitas,L. Lankester,Christine A. Wells,A. S. Raj,Katherine Fletcher,R. Khade,G. Tsinaslanidis,Michael MacMahon,Stephen J. Fowler,T. Coventry,Richard B. Stewart,L. Wren,E. Mwaura,L. Mew,D. Scaletta,Frances M K Williams,K. Inweregbu,N. Lancaster,Matthew Cunningham,A. Daniels,L. Harrison,S. Hope,S Jones,A. Crew,G. Wray,John N. S. Matthews,R. Crawley,J. Carter,I. Birkinshaw,J. Ingham,Z. Scott,H. Pearson,K. Howard,R. Joy,S. Roche,M. Clark,S. Purvis,Alanna C. Morrison,David P. Strachan,S. Clements,K. Black,Chetan Parmar,A. Altabaibeh,Kenneth J. Simpson,L. Mostoles,K. Gilbert,L. Ma,A. Alvaro,Mark G. Thomas,B. Faulkner,R. Worner,Kate Hayes,E. Gendall,H. Blakemore,B. Borislavova,E. Goff,Alan Vuylsteke,L. Mwaura,J. Zamikula,L Garner,A. Mitchell,S. Mepham,L. Cagova,A. Fofano,H. Holcombe,K. Praman,Tamas Szakmany,A. E. Heron,S. Cherian,S. Cutler,A. Roynon-Reed,G. Randell,K. Convery,K. Stammers,D. Fottrell-Gould,L. Hudig,J. Keshet-Price,Mark J. Peters,L. O'Neill,Swapan K. Ray,H. Belfield,T. McHugh,Graeme Jones,O. Akinkugbe,A. Tomas,E. Abaleke,E. Beech,H. Meghari,S. Yussuf,A. Bamford,B. Hairsine,E. Dooks,F. Farquhar,S. Packham,H. Bates,Lawrence Armstrong,C. Kaye,A. Allan,J. Medhora,J. Liew,A. Botello,F. Anderson,Rebecca Cusack,H. Golding,K. Prager,Thomas N. Williams,S. Leggett,K. Golder,M. Male,O. Jones,K. Criste,M. Marani,V. Anumakonda,V. Amin,K. Karthik,R. Kausar,E. Anastasescu,K. Reid,Mari Smith,Anil Hormis,Rosie M. Walker,T. Duncan,A. Uriel,Andrew Ustianowski,H. T-Michael,M. Bruce,K. Connolly,Kenneth Smith,Roland Partridge,Darren K. Griffin,M. Mupudzi,N. Muchenje,Dori-Ann Martin,H. Filipe,C. Eastgate,C. Jackson,Andrew Gratrix,L. Foster,Victoria Martinson,E. Stones,C. Abernathy,P. Parkinson,A. Reed,C. Prendergast,Peter Rogers,M. Woodruff,R. Shokkar,S Kaul,A. Barron,C. Collins,S. Beavis,A. Whileman,K. Dale,J. Hawes,K. Pritchard,R. Gascoyne,L. Stevenson,R. Jha,L. Lim,V. Krishnamurthy,Roy Parker,I. Turner-Bone,L. Wilding,A. Reddy,S. Whiteley,E. Wilby,C. Howcroft,A. Aspinwall,Sue Charlton,B. Ogg,Donna J. Menzies,Richard Pugh,E. Allan,R. Lean,F. Davies,J. Easton,X. Qiu,Shriya B. Kumar,K. Darlington,G. Houston,P. O'Brien,T. Geary,Jay Allan,A. Meikle,Grant L. Hughes,M. Balasubramaniam,S. Latham,E. McKenna,R. Flanagan,S. Sathe,Emma L. Davies,M. Chablani,A. Kirkby,K. Netherton,S. Archer,Bryan Yates,C. Ashbrook-Raby,Sarah Cole,M. Casey,L. Cabrelli,Stephen Chapman,A. Hutcheon,C. Whyte,C. Almaden-Boyle,Natalie Pattison,Claudina Cruz,A. Vochin,H. Kent,Adri A. M. Thomas,S. Murdoch,B. David,M. Penacerrada,G. Lubimbi,V. Bastion,R. Wulandari,Roberto Lorusso,J. Valentine,D. Clarke,A. Serrano-Ruiz,S. Hierons,C. Eckbad,L. Ramos,C. Demetriou,S. Mitchard,K. White,Nicholas J. White,Steven J. Pitts,D. Branney,J. Frankham,M. Watters,H. Langton,Rachel Prout,V. Page,T. Varghes,A. Cowton,A. Kay,K. Potts,M. Birt,Matthew Peter Kent,A. Wilkinson,E. B. Jude,V. Turner,H. Savill,J. McCormick,M. Coulding,S. Siddiqui,O. Mercer,H. Rehman,D. Potla,N. Capps,David S. Donaldson,H. Button,Terry Martin,K. Hard,A. Agasou,L. Tonks,T. Arden,Patricia A. Boyle,M. Carnahan,J. Strickley,Christopher M. Adams,D. Childs,R. Rikunenko,M. Leigh,M. Breekes,R. Wilcox,A. Bowes,H. Tiveran,F. Hurford,J. Summers,Austin Carter,Y. Hussain,L. Ting,A. Javaid,N. Motherwell,H. Moore,H. Millward,S. Jose,N. Schunki,A. Noakes,C. Clulow,G. Sadera,Reni Jacob,Chris Jones,M. Blunt,Z. Coton,H. Curgenven,S. M. Ally,K. Beaumont,M. Elsaadany,K. Fernandes,I. Ali Mohamed Ali,H. Rangarajan,V. Sarathy,S. Selvanayagam,D. Vedage,M. White,N. Truman,Srikanth Chukkambotla,S. Keith,J. Cockerill-Taylor,J. Ryan-Smith,R. Bolton,P. Springle,J. Dykes,Jo Thomas,Muzamil Majid Khan,M. T. Hijazi,E. Massey,G. Croston,Henrik Reschreiter,Julie Camsooksai,S. Patch,S. Jenkins,C. Humphrey,B. Wadams,M. Msiska,O. Adanini,B. Attwood,P. Parsons,Kate Tatham,S. Jhanji,E. Black,A. Dela Rosa,R. Howle,B. Thomas,T. Bemand,R. Raobaikady,R. Saha,Nikki Staines,A. Daniel,J. Finn,J. Hutter,P. Doble,C. Shovelton,C. Pawley,T. Kannan,Michael Hill,E. Combes,S. Monnery,T. Joefield,M. Popescu,M. Thankachen,M. Oblak,Jeff Little,S. McIvor,A. Brady,H. Whittle,H. Prady,R. Chan,A. Ahmed,Andrew D. Morris,C. Gibson,E. Gordon,S. Keenan,H. Quinn,S. Benyon,S. Marriott,L. Zitter,L. Park,K. Baines,M. Lyons,M. Holland,N. Keenan,M. Young,S. Garrioch,J. Dawson,M. Tolson,B. Scholefield,R. Bi,Neil Richardson,N. Schumacher,T. Cosier,G. Millen,A. Higham,S. Turki,L. Allen,N. Crisp,T. Hazleton,A. Knight,J. Deery,C. Price,S. Turney,S. Tilbey,E. Beranova,Derek W. Wright,L. George,S. Twiss,S. Wadd,K. Postlethwaite,P. Gondo,B. Masunda,A. Kayani,B. Hadebe,J. Whiteside,N. Clarke,Phil Donnison,F. Trim,I. Leadbitter,D. Butcher,S. O'Sullivan,B. Purewal,Scott C. Bell,V. Rivers,R. O'Leary,J. Birch,E. Collins,Stephen K. Anderson,K. Hammerton,E. Andrews,K. Burns,I. Edmond,A. Todd,J. Donnachie,P. Turner,L. Prentice,L. Symon,N. Runciman,F. Auld,M. Halkes,P. Mercer,L. Thornton,G. Debreceni,J. Wilkins,V. Crickmore,G. Subramanian,Robert Marshall,C. Jennings,M. Latif,L. Bunni,M. Spivey,S. Bean,K. Burt,Vanessa Linnett,J. Ritzema,A. Sanderson,W. McCormick,M. Bokhari,R. Kapoor,D. Loader,A. Ayers,W. Harrison,J. North,Z. Belagodu,R. Paramsothy,O. Olufuwa,A. Gherman,B. Fuller,C. Stuart,O. Kelsall,Carrie A. Davis,L. Wild,Henry Wood,Jessica Thrush,A. Durie,K. Austin,K. Archer,P. Anderson,C. Vigurs,C. Thorpe,E. Knights,N. Boyle,Alkes L. Price,A. Kubisz-Pudelko,D. Wood,Amy Lewis,S. Board,L. Pippard,John R. B. Perry,K. Beesley,A. Rattray,E. Lee,L. Lennon,K. Douglas,D. Bell,R. Boyle,L. Glass,M. Nauman Akhtar,K. Dent,D. Potoczna,S. Pearson,E. Horsley,S. Spencer,D. Mullan,D. Skinner,J. Gaylard,R. Barber,C. Hewitt,A. Hilldrith,S. Shepardson,M. Wills,K. Jackson-Lawrence,A. Gupta,E. Timlick,C. Gorman,Igor Otahal,A. Gales,S. Coetzee,Christian Sell,M. Raj,M. Peiu,S. Quaid,E. Watson,Katherine S. Elliott,J. Mallinson,B. Chandler,A. Turnbull,C. Finch,C. Holl,J.A. Cooper,Anthony Evans,W. Khaliq,Andrea M. Collins,E. T. Gude,N. Love,L. van Koutrik,John A. Hunt,D. Kaye,Eva Fisher,A. Brayne,V. Tuckey,P. Jackson,J. Parkin,A. Tariq,Henry Houlden,A. Tucci,John Hardy,E. Moncur,J. Highgate,A. Cowley,A. Mitra,R. Stead,T. Behan,C. Burnett,M. Newton,E. Heeney,R. Pollard,J. Hatton,Amita Patel,Vidya Kasipandian,S. Allibone,R. M. Genetu,L. O'Brien,Z. Omar,E. Perkins,Kevin A. Davies,D. Tetla,B. Shelley,V. Irvine,Samantha J. Williams,Patricia Williams,J. Goodsell,R. Tutton,L. Bough,B. Winter-Goodwin,R. Kitson,J. Pinnell,Anthony J. Wilson,T. Nortcliffe,T. Wood,M. Home,K. Holdroyd,Matthew R. Robinson,R. Shaw,J. Greig,M. Brady,A. Haigh,L. Matupe,M. Usher,S. Mellor,S. Dale,L. Gledhill,L. Shaw,G. Turner,Donna Kelly,B. Anwar,Heather L. Riley,H. Sturgeon,A. Ali,L. Thomis,D. Melia,A. Dance,SE Humphreys,I. Frost,V. Gopal,Jo Godden,A. Holden,S. Swann,Tony Smith,M. Clapham,U. Poultney,R. Harper,P. Rice,R. Reece-Anthony,B. Gurung,S. Moultrie,M. Odam,Andreas Mayer,A. Bellini,A. Pickard,J. Bryant,N. Roe,J. Sowter,K. Lang,Jenny C. Taylor,P. Barry,Maria Hobrok,H. Tench,R. Wolf-Roberts,H. McGuinness,R. Loosley,Daniel B Hawcutt,L. Rad,L. O'Malley,P. Saunderson,G. Seddon,Tim J. Anderson,N. Rogers,J. Ruddy,M. Harkins,C. Beith,A. McAlpine,L. Ferguson,Paul Grant,S. MacFadyen,M. McLaughlin,T. Baird,S. Rundell,B. Welsh,R. Hamill,F. Fisher,J. Gregory,Campbell A,S. Smuts,J Kenneth Baillie,J Kenneth Baillie,Gail Carson,Beatrice Alex,B. Bach,Wendy S. Barclay,Debby Bogaert,Meera Chand,Graham S Cooke,Annemarie B Docherty,Jake Dunning,A. da Silva Filipe,Tom Fletcher,Christopher A Green,Ewen M Harrison,Julian A. Hiscox,Ho A. Y. W.,Peter Horby,Samreen Ijaz,S. Khoo,W. S. Lim,Alexander J. Mentzer,Laura Merson,Alison M. Meynert,Mahdad Noursadeghi,Massimo Palmarini,William A. Paxton,Georgios Pollakis,Nicholas Price,Andrew Rambaut,David Robertson,Vanessa Sancho-Shimizu,Janet T Scott,T I de Silva,Louise Sigfrid,Tom Solomon,Shiranee Sriskandan,David I. Stuart,R.S. Tedder,E. Thomson,Alfred A.R. Thompson,Ryan S Thwaites,L Turtle,Maria Zambon,Hayley Hardwick,Chloe Donohue,Ronan A Lyons,Lisa Norman,Riinu Pius,Thomas M Drake,Cameron J Fairfield,Stephen R Knight,Kenneth A. McLean,Derek Murphy,C. A. Shaw,Jo Dalton,Michelle Girvan,Egle Saviciute,Stuart K. Roberts,Janet Harrison,Laura Marsh,Marie Connor,Sophie Halpin,Carrol Gamble,Gary Leeming,Murray Wham,William Greenhalf,V. Shaw,Sarah D. McDonald,Andrea Ganna,Patrick Sulem,D A van Heel,M. Cordioli,Gardar Sveinbjornsson,M. E. K. Niemi,Janie F. Shelton,A. J. Shastri,C. Ye,C. H. Weldon,T. Filshtein-Sonmez,D. Coker,A. Symons,J. Esparza-Gordillo,Stella Aslibekyan,Adam Auton,J. E. Krieger,E. Marques,C. E. Jannes,Francesca Mari,S. Daga,Margherita Baldassarri,Elisa Benetti,Simone Furini,Chiara Fallerini,Francesca Fava,Floriana Valentino,G. Doddato,Annarita Giliberti,Rossella Tita,Sara Amitrano,Mirella Bruttini,S. Croci,I. Meloni,A. M. Pinto,E. Frullanti,Maria Antonietta Mencarelli,C. L. Rizzo,Francesca Montagnani,L. Di Sarno,A. Tommasi,Marta Palmieri,Arianna Emiliozzi,M. Fabbiani,Barbara Rossetti,Giacomo Zanelli,Elena Bargagli,Laura Bergantini,Miriana d'Alessandro,Paolo Cameli,D. Bennet,Federico Anedda,Simona Marcantonio,Sabino Scolletta,Federico Franchi,Maria Antonietta Mazzei,S. Guerrini,Edoardo Conticini,Luca Cantarini,Bruno Frediani,D. Tacconi,C. Spertilli,M. Feri,Abele Donati,R. Scala,L. Guidelli,G. Spargi,M. Corridi,C. Nencioni,L. Croci,G. P. Caldarelli,M. Spagnesi,P. Piacentini,M. Bandini,E. Desanctis,S. Cappelli,A. Canaccini,A. Verzuri,V. Anemoli,A. Ognibene,M. Vaghi,A d'Arminio Monforte,Esther Merlini,M. U. Mondelli,S. Mantovani,S. Ludovisi,Massimo Girardis,S. Venturelli,M. Sita,Andrea Cossarizza,A. Antinori,Alessandra Vergori,Stefano Rusconi,M. Siano,A. Gabrieli,Agostino Riva,Daniela Francisci,Elisabetta Schiaroli,P. G. Scotton,F. Andretta,S. Panese,R. Scaggiante,F. Gatti,S. G. Parisi,Francesco Castelli,M. E. Quiros-Roldan,P. Magro,Isabella Zanella,M. Della Monica,Carmelo Piscopo,Mario Capasso,Roberta Russo,Immacolata Andolfo,Achille Iolascon,G. Fiorentino,M. Carella,Marco Castori,Giuseppe Merla,Filippo Aucella,P. Raggi,C. Marciano,R. Perna,Matteo Bassetti,A. Di Biagio,M. Sanguinetti,L. Masucci,Serafina Valente,Marco Mandalà,A. Giorli,L. Salerni,P. Zucchi,P. Parravicini,E. Menatti,S. Baratti,T. Trotta,F. Giannattasio,G. Coiro,F. Lena,D. A. Coviello,Cristina Mussini,G. Bosio,E. Martinelli,Sandro Mancarella,L. Tavecchia,L. Crotti,N. Picchiotti,M. Gori,C. Gabbi,M. Sanarico,S. Ceri,P. Pinoli,F. Raimondi,F. Biscarini,A. Stella,Xia Shen,Xia Shen,Chris P. Ponting,Angie Fawkes,Albert Tenesa,Albert Tenesa,Mark J. Caulfield,Richard H Scott,K Rowan,Lee Murphy,Peter J. M. Openshaw,Peter J. M. Openshaw,Malcolm G Semple,Veronique Vitart,James F. Wilson +1449 more
TL;DR: The GenOMICC (Genetics Of Mortality In Critical Care) genome-wide association study in 2244 critically ill Covid-19 patients from 208 UK intensive care units is reported, finding evidence in support of a causal link from low expression of IFNAR2, and high expression of TYK2, to life-threatening disease.
Journal ArticleDOI
HIV-1 remission following CCR5Δ32/Δ32 haematopoietic stem-cell transplantation
Ravindra K. Gupta,Sultan Abdul-Jawad,Laura E. McCoy,Hoi Ping Mok,Dimitra Peppa,Maria Salgado,Javier Martinez-Picado,Javier Martinez-Picado,Monique Nijhuis,Annemarie M. J. Wensing,Helen Lee,Paul Grant,Eleni Nastouli,Jonathan Lambert,M Pace,Fanny Salasc,Christopher Monit,Andrew J. Innes,Andrew J. Innes,Luke Muir,Laura Waters,John Frater,Andrew M. L. Lever,Andrew M. L. Lever,Simon Edwards,Ian H Gabriel,Ian H Gabriel,Eduardo Olavarria,Eduardo Olavarria +28 more
TL;DR: It is suggested that a single allogeneic HSCT with homozygous CCR5Δ32 donor cells may be sufficient to achieve HIV-1 remission with reduced intensity conditioning and no irradiation, and the findings provide further support for the development of HIV- 1 remission strategies based on preventing CCR 5 expression.
Journal ArticleDOI
Diagnosis of neuroinvasive astrovirus infection in an immunocompromised adult with encephalitis by unbiased next-generation sequencing
Samia N. Naccache,Karl S. Peggs,Frank M. Mattes,Rahul Phadke,Jeremy A. Garson,Paul Grant,Erik Samayoa,Scot Federman,Steve Miller,Michael P. Lunn,Vanya Gant,Charles Y. Chiu +11 more
TL;DR: The sequencing and confirmatory studies revealed neuroinvasive infection of the brain by an astrovirus belonging to a recently discovered VA/HMO clade.
Journal ArticleDOI
SARS-CoV-2 Omicron is an immune escape variant with an altered cell entry pathway
Brian J. Willett,Joe Grove,Oscar A. MacLean,Craig Wilkie,Giuditta De Lorenzo,Wilhelm Furnon,Diego Cantoni,S. Scott,Nicola S Logan,Shirin Ashraf,M. Manali,Agnieszka M. Szemiel,Vanessa M. Cowton,Elen Vink,Chris Davis,Patawee Asamaphan,Richard J. Orton,P Holland,Vanessa Silva,David J Pascall,Kathryn Puxty,Sharif Shaaban Muhammad Shaaban,Matthew T. G. Holden,Rute Maria Pinto,Kate Templeton,Pablo R. Murcia,Arvind H. Patel,Paul Klenerman,Susanna Dunachie,Eleanor Barnes,Anthony Brown,S Adele,Barbara Kronsteiner,Sam M. Murray,P. Abraham,Alexandra Deeks,M A Ansari,Lance Turtle,Shona C Moore,James Austin,Alex G. Richter,Christopher J A Duncan,Rebecca Payne,Amy Ehrlich Ash,C. J. Koshy,Beatrix Kele,Teresa Cutino-Moguel,Derek Fairley,James McKenna,Tanya Curran,Helen Adams,Christophe Fraser,David Bonsall,Helen R. Fryer,Katrina A. Lythgoe,Laura Hayden Thomson,Tanya Golubchik,Abigail Murray,D. Singleton,Shaun M. Beckwith,A Mantzouratou,Magdalena Barrow,Sarah L. Buchan,Nicola Reynolds,Ben Warne,Joshua Maksimovic,Karla Spellman,Kathryn Mccluggage,M. John,Robert H. Beer,Safiah Afifi,Sian Natasha Morgan,Andrew L. Mack,Angela Marchbank,Anna Price,A.C. Morriss,Catherine Bresner,Christine Kitchen,I. Merrick,Joel Southgate,Martyn F Guest,Owen Bowden Jones,Robert F. Munn,Thomas R. Connor,Tom Whalley,T. Race Workman,William Oliver Fuller,Amita Patel,Bindi Patel,G. Nebbia,Jonathan D. Edgeworth,Luke B Snell,Rahul Batra,Themoula Charalampous,Angela Helen Beckett,Ekaterina Shelest,Samuel Robson,Anthony Underwood,Benjamin Taylor,Corin Yeats,David M. Aanensen,Khalil Abudahab,Mirko Menegazzo,Amelia Joseph,Gemma Clark,Hannah C. Howson-Wells,Louise Berry,Manjinder Khakh,Michelle Lister,T. Boswell,Vicki M. Fleming,Christopher W Holmes,Claire McMurray,Jessica R. Shaw,Julian W. Tang,Karlie Fallon,Minaxshi Odedra,Nicholas J. Willford,Paul W Bird,Thomas Helmer,L.A. Williams,Nicole R. Sheriff,Sharon Campbell,Veena Raviprakash,Vickie L. Blakey,Christopher I. Moore,Fei Sang,Johnny Debebe,Matthew Carlile,Matthew Loose,Nadine Holmes,Victoria Wright,M. Torok,William L Hamilton,Alessandro M Carabelli,Andrew Jermy,Beth Blane,Carol Churcher,Catherine Ludden,Dinesh Aggarwal,Elaine J. Westwick,Ellen Brigid Brooks,Georgina M. McManus,Katerina Galai,Ken R. Smith,Kim Smith,MacGregor Cox,Mireille Fragakis,Patrick Maxwell,Sarah Judges,Sharon J. Peacock,Theresa Feltwell,A. K. Kenyon,Sahar Eldirdiri,Thomas Davis,Joshua F. Taylor,NgeeKeong Tan,Alexander E. Zarebski,Bernardo Gutierrez,Jayna Raghwani,Louis du Plessis,Moritz U. G. Kraemer,Oliver G. Pybus,Sarah François,S. W. Attwood,Tetyana I. Vasylyeva,Aminu S Jahun,Ian Goodfellow,Iliana Georgana,Malte L Pinckert,Myra Hosmillo,Rhys E. Izuagbe,Yasmin Chaudhry,Felicity Ryan,Hannah Louise Lowe,Samuel Rajan Moses,Luke Bedford,James S Cargill,Warwick S. Hughes,J. Moore,Susanne Stonehouse,Divya Shah,Jack Lee,Julianne R Brown,Kathryn A. Harris,Laura Atkinson,Nathaniel Storey,Moira J. Spyer,Flavia Flaviani,Adela Alcolea-Medina,J. Sehmi,John Ramble,Natasha Ohemeng-Kumi,P. Smith,B. Bertolusso,Claire P Thomas,Gabrielle Vernet,Jessica Lynch,Nathan Moore,Nicholas Cortes,Rebecca Williams,Stephen P. Kidd,L. J. Levett,Monika Pusok,Paul Grant,Stuart Kirk,W. J. Chatterton,Li Xu-McCrae,Darren L. Smith,Gregor Young,Matthew Bashton,Katie Kitchman,Kavitha Gajee,K. Eastick,Patrick J. Lillie,Phillipa Burns,William G. Everson,Alison Cox,Alison Holmes,Frances Bolt,James R. Price,Marcus Pond,Paul Randell,Pinglawathee Madona,Siddharth Mookerjee,Erik M. Volz,Lily Geidelberg,Manon Ragonnet-Cronin,Olivia Boyd,Robert Johnson,Cassie F Pope,Adam A. Witney,Irene M. Monahan,Ken Laing,Katherine Smollett,Alan McNally,Joanne Stockton,Joshua Quick,Nicholas J. Loman,Radoslaw Poplawski,Samuel M. Nicholls,Will P. M. Rowe,Anibolina Castigador,Emily Macnaughton,Kate El Bouzidi,Malur Sudhanva,Temi Lampejo,Rocio Martinez Nunez,Cathy Breen,Graciela Sluga,Karen T. Withell,Nicholas W Machin,Ryan George,Shazaad Ahmad,David Pritchard,D. Binns,Nick Wong,Victoria L. James,Cheryl Williams,Christopher J. R. Illingworth,Christopher Jackson,Daniela De Angelis,Afrida Mukaddas,Alice Broos,Ana da Silva Filipe,Daniel Mair,David Robertson,Derek W. Wright,E. Thomson,Igor Starinskij,Ioulia Tsatsani,James Shepherd,Jenna Nichols,Joseph Hughes,Kyriaki Nomikou,Lily Tong,Sreenu B. Vattipally,William T. Harvey,Roy A. Sanderson,S. O’Brien,Steven Rushton,Jon Davis Perkins,Rachel Blacow,Rory Gunson,A. Gallagher,Elizabeth Wastnedge,Martin P McHugh,Rebecca Dewar,Seb Cotton,Lindsay Coupland,R.Suganya and Dr. Shaleesha A. Stanley,Samir Dervisevic,Lewis G. Spurgin,Louise Smith,Clive Graham,D. Padgett,Edward Barton,Garren Scott,Aidan Cross,Mariyam Mirfenderesky,E. Swindells,J Greenaway,Rebecca Denton-Smith,Robyn Turnbull,Giles Idle,Kevin Cole,Amy Louise Hollis,Andrew T. Nelson,C. McCann,Joan H Henderson,M. Crown,Wen Chyin Yew,W Stawski Stanley,Nicholas Duckworth,Phillip Clarke,Sarah Walsh,Tim J. Sloan,Kelly Bicknell,R. L. Impey,Sarah Wyllie,Scott M. Elliott,Sharon Glaysher,Declan Bradley,Nicholas Killough,Tim W. Wyatt,Andrew Bosworth,Barry Vipond,Clare Pearson,Elias Allara,E. E Robinson,Hannah M. Pymont,Husam Osman,Peter C. Muir,Richard Hopes,S. A. Hutchings,Martin D. Curran,Surendra S. Parmar,A Thornton,Angie Lackenby,Chloe Bishop,David F. Bibby,Dave Lee,Eileen Gallagher,Gavin Dabrera,Ian Harrison,Jonathan Hubb,Katherine A. Twohig,Meera Chand,Nicholas Ellaby,Nikos Manesis,R. Myers,Steven Platt,Tamyo Mbisa,Vicki Chalker,Gonzalo Yebra,Stefan Rooke,Alec Birchley,Alexander Adams,A Davies,Amy E. Gaskin,Bree Gatica-Wilcox,Caoimhe McKerr,Catherine Moore,Catryn Williams,Chris Williams,David Heyburn,Elen de Lacy,Ember Hilvers,Fatima Downing,Georgia Pugh,Hannah Jones,Hibo Asad,Jason D. Coombes,Jessica G. Hey,Jessica L. Powell,Joanne Watkins,John Evans,Laia Fina,Laura Gifford,L Gilbert,Lee H. Graham,Malorie Perry,Mari Morgan,Matthew Bull,Nicole Pacchiarini,Noel Craine,Sally Corden,Sara Kumžiene-Summerhayes,Sara Rey,Sarah Taylor,Simon Cottrell,Sophie Jones,Sue Edwards,Tara Annett,Alexander J. Trotter,Alison E. Mather,Alp Aydin,Andrew J. Page,David J. Baker,Ebenezer Foster-Nyarko,Gemma L. Kay,Justin O'Grady,Leonardo de Oliveira Martins,Lizzie Meadows,Nabil-Fareed Alikhan,Sophie J Prosolek,Steven J. Rudder,Thanh Le-Viet,Anna Casey,Liz Ratcliffe,Aditi Singh,Arun Mariappan,Chris L. Baxter,Clara Radulescu,David Simpson,Debra Redman Lavin,Fiona Rogan,Julia Miskelly,Marc Fuchs,Miao Tang,Sílvia F. Carvalho,Stephen Bridgett,Timofey Skvortsov,Zoltán Molnár,Newara Ramadan,Bridget A. Knight,Christopher R. Jones,Cressida Auckland,Helen Morcrette,Jennifer Lee Poyner,Dianne Irish-Tavares,Eric Witele,Jennifer Hart,Tabitha Mahungu,Tanzina Haque,Yann Bourgeois,Christopher Fearn,Kate Cook,Katie F. Loveson,Salman Goudarzi,Cariad Evans,David G Partridge,Katie Johnson,Mehmet Yavus,Mohammad Raza,Craig Mower,Paul Baker,Sarah Essex,Stephen Bonner,Leanne Murray,Louisa K. Watson,Steven P. Liggett,Andrew I. Lawton,Ronan A Lyons,Brendan A I Payne,G Eltringham,Jennifer Collins,Sheila Waugh,Shirelle Burton-Fanning,Yusri Taha,Christopher Jeanes,Andrea N. Gomes,Darren Murray,Maimuna Kimuli,D Dobie,Paula Ashfield,Angus I. Best,Benita Percival,Emma Moles-Garcia,F. Ashford,Jeremy Mirza,L. Crawford,Megan Mayhew,Nicola Cumley,Oliver Megram,Dan Frampton,Judith Heaney,Matthew Byott,C. Houlihan,Charlotte A Williams,Eleni Nastouli,Helen Lowe,John A. Hartley,Judith Breuer,Laurentiu Maftei,Leah Ensell,Marius Cotic,Matteo Mondani,Molly Driscoll,N. Bayzid,Rachel Williams,Sunando Sur Roy,Adhyana I K Mahanama,Buddhini Samaraweera,Eleri Wilson-Davies,Emanuela Pelosi,H.C Umpleby,Helen Wheeler,Jacqui Prieto,Kordo Saeed,Matthew Harvey,Sarah Jeremiah,Siona Silviera,Stephen Aplin,T. Sass,BS Macklin,Dorian Crudgington,Liz Sheridan,Benjamin J. Cogger,Cassandra Malone,Florence Munemo,Hannah Huckson,Jonathan Lewis,Lisa J. Easton,Manasa Mutingwende,Michelle J. Erkiert,Mohammed O. Hassan-Ibrahim,N. Chaloner,Olga Podplomyk,Paul Randell,Roberto Nicodemi,Sarah L. Lowdon,Thomas Somassa,Andrew Beggs,Andrew Hesketh,Colin P. Smith,Giselda Bucca,Christopher Ruis,Claire Cormie,Ellen E. Higginson,Jamie Young,Joana Dias,L. Kermack,Mailis Maes,Ravi Gupta,Sally Forrest,Sophia T. Girgis,Rose K Davidson,Áine O'Toole,Andrew Rambaut,Ben Jackson,Carlos Balcazar,Daniel S. Maloney,Emily Scher,J. McCrone,Katherine A. Williamson,Michael D. Gallagher,Nathan C Medd,Rachel M. Colquhoun,Thomas D. Stanton,Thomas C Williams,Verity Hill,Aaron R. Jeffries,Ben Temperton,Christine Sambles,David J. Studholme,Joanna Warwick-Dugdale,Leigh Jackson,Michelle Michelsen,R. Manley,Stephen L. Michell,Alistair C. Darby,Anita Lucaci,Charlotte Nelson,Claudia Wierzbicki,Edith E. Vamos,Hermione J. Webster,Kathryn A. Jackson,Lucille Rainbow,Margaret Lawrence Hughes,Mark Whitehead,Matthew Gemmell,Miren Iturriza-Gomara,Richard Eccles,Richard Gregory,Sam Haldenby,Steve Paterson,Adrienn Angyal,Alexander J Keeley,Benjamin Foulkes,Benjamin B Lindsey,Dennis Wang,Hailey Hornsby,Luke R. Green,Manoj Baliram Pohare,M. Gallis,Matthew Parker,M. Whiteley,Nikki Smith,P. Wolverson,Peijun Zhang,Samantha Hansford,Sharon N. Hsu,S. Louka,Thushan I de Silva,Timothy M. Freeman,Matilde Mori,Emily J. Park,Jack Hill,Jayasree Dey,Jonathan K. Ball,Joseph G. Chappell,Patrick McClure,Timothy Byaruhanga,A Fanaie,Geraldine Yaze,Rachel A. Hilson,Amy Trebes,Angie Green,David Buck,G. Macintyre-Cockett,John A. Todd,Andrew R. Bassett,Andrew Whitwham,Cordelia Langford,Diana Rajan,Dominic P. Kwiatkowski,J. Harrison,Iraad F. Bronner,Jaime M. Tovar-Corona,Jennifier Liddle,Jillian Durham,Katherine L. Bellis,Kevin Lewis,Louise Aigrain,Nicholas Redshaw,Robert L. Davies,Robin J. Moll,Shane A. McCarthy,Stefanie V Lensing,Steven Leonard,Ben Farr,C. Scott,Charlotte M. Beaver,Cristina V. Ariani,Da Weldon,David Jackson,Emma Betteridge,Gerry Tonkin-Hill,Ian Johnston,Inigo Martincorena,James K. Bonfield,Jeffrey C. Barrett,John Sillitoe,J P Keatley,Karen A. Oliver,Keith James,Lesley Shirley,Liam J. Prestwood,Luke Foulser,Marina Gourtovaia,Matthew J. Dorman,Michael A. Quail,Michael Spencer Chapman,Naomi Park,Rich Livett,Roberto Amato,Sally Kay,Scott Goodwin,Scott Thurston,Shavanthi Rajatileka,Sónia Gonçalves,Stephanie Lo,Theo Sanderson,Alasdair MacLean,Emily Goldstein,Lynne Ferguson,Rachael M. Tomb,Jana Catalan,Neil Jones,John Haughney,Massimo Palmarini,Surajit Ray +672 more
TL;DR: In this article , the authors demonstrate substantial evasion of neutralization by Omicron BA.1 and BA.2 variants in vitro using sera from individuals vaccinated with ChAdOx1, BNT162b2 and mRNA-1273.529.
Journal ArticleDOI
Full-genome deep sequencing and phylogenetic analysis of novel human betacoronavirus.
Matthew Cotten,Tommy T-Y Lam,Simon J. Watson,Anne L. Palser,Velislava N. Petrova,Paul Grant,Oliver G. Pybus,Andrew Rambaut,Yi Guan,Deenan Pillay,Paul Kellam,Eleni Nastouli +11 more
TL;DR: Molecular clock analysis showed that the 2 human infections of this betacoronavirus in June 2012 and September 2012 share a common virus ancestor most likely considerably before early 2012, suggesting the human diversity is the result of multiple zoonotic events.