Steven Zacks

TL;DR: In this article, the authors present characteristics and subgroup analyses from the first 1257 patients enrolled in the study, and conclude that there are no differences in outcomes of patients with short vs long latency of DILI.

TL;DR: The data suggest that ISG inducibility is important for the treatment response and that ribavirin may improve outcomes by enhancing hepatic gene responses to peginterferon, and these mechanisms may provide a molecular basis for the improved efficacy of combination therapy.

TL;DR: HPS was associated with a significant increase in risk of death as well as worse functional status and quality of life in patients evaluated for liver transplantation.

TL;DR: Female sex and autoimmune hepatitis were associated with an increased risk of portopulmonary hypertension, whereas hepatitis C infection was associated with a decreased risk in patients with advanced liver disease, suggesting Hormonal and immunologic factors may be integral to the development ofportopul pulmonary hypertension.

TL;DR: Genetic variation in estrogen signaling and cell growth regulators is associated with the risk of portal hypertension in patients with advanced liver disease and these biologic pathways may elucidate the mechanism for the development of PPHTN in certain patients with severe liver disease.