S
Suhan Lee
Researcher at University of California, San Diego
Publications - 4
Citations - 461
Suhan Lee is an academic researcher from University of California, San Diego. The author has contributed to research in topics: Liver injury & Liver disease. The author has an hindex of 2, co-authored 4 publications receiving 229 citations.
Papers
More filters
Journal ArticleDOI
Bacteriophage targeting of gut bacterium attenuates alcoholic liver disease
Yi Duan,Yi Duan,Cristina Llorente,Cristina Llorente,Sonja Lang,Katharina Brandl,Huikuan Chu,Lu Jiang,Lu Jiang,Richard C. White,Thomas H. Clarke,Kevin Nguyen,Manolito Torralba,Yan Shao,Jinyuan Liu,Adriana Hernandez-Morales,Lauren Lessor,Imran R Rahman,Yukiko Miyamoto,Melissa Ly,Bei Gao,Weizhong Sun,Roman Kiesel,Felix Hutmacher,Suhan Lee,Meritxell Ventura-Cots,Francisco Bosques-Padilla,Elizabeth C. Verna,Juan G. Abraldes,Robert S. Brown,Victor Vargas,José Altamirano,Juan Caballería,Debbie L. Shawcross,Samuel B. Ho,Samuel B. Ho,Alexandre Louvet,Michael R. Lucey,Philippe Mathurin,Guadalupe Garcia-Tsao,Ramon Bataller,Xin M. Tu,Lars Eckmann,Wilfred A. van der Donk,Ry Young,Trevor D. Lawley,Peter Stärkel,David T. Pride,Derrick E. Fouts,Bernd Schnabl,Bernd Schnabl +50 more
TL;DR: It is shown that bacteriophages can specifically target cytolytic E. faecalis, which provides a method for precisely editing the intestinal microbiota, and is linked with more severe clinical outcomes and increased mortality in patients with alcoholic hepatitis.
Journal ArticleDOI
The Role of Intestinal C‐type Regenerating Islet Derived‐3 Lectins for Nonalcoholic Steatohepatitis
Sena Bluemel,Lirui Wang,Cameron Martino,Suhan Lee,Yanhan Wang,Brandon Williams,Angela Horvath,Vanessa Stadlbauer,Karsten Zengler,Bernd Schnabl +9 more
TL;DR: In contrast to alcoholic liver disease, loss of intestinal Reg3 lectins is not sufficient to aggravate diet‐induced obesity and NASH, which supports a multi‐hit pathogenesis in NASH.
Journal ArticleDOI
Tumor necrosis factor alpha receptor 1 deficiency in hepatocytes does not protect from non-alcoholic steatohepatitis, but attenuates insulin resistance in mice.
TL;DR: The results indicate that deficiency of TNFR1 signaling in hepatocytes does not protect from diet-induced NASH, however, improved insulin resistance in this model strengthens the role of the liver in glucose homeostasis.
Targeted use of siRNA in animal models of hepatic damage: an innovative therapy for acute liver failure
Guadalupe Garcia-Tsao,Ronald P.J. Oude Elferink,Suhan Lee,Wang J,Ince N,Jianliang Chen,Shankar P,Tillmann Hl,Zender S,B. Mundt,M Waltemathe,Gosling T,Flemming P,Christian Trautwein +13 more
TL;DR: Investigation of the in vivo silencing effect of small interfering RNA (siRNA) duplexes targeting the gene Fas to protect mice from liver failure and fibrosis in two models of autoimmune hepatitis found therapeutic promise to prevent liver injury by protecting hepatocytes from cytotoxicity.