S
Suman Wang
Researcher at University of Science and Technology of China
Publications - 6
Citations - 60
Suman Wang is an academic researcher from University of Science and Technology of China. The author has contributed to research in topics: RNA recognition motif & Telomere. The author has an hindex of 2, co-authored 4 publications receiving 26 citations.
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Journal ArticleDOI
ZBTB10 binds the telomeric variant repeat TTGGGG and interacts with TRF2.
Alina Bluhm,Nikenza Viceconte,Fudong Li,Grishma Rane,Sandra Ritz,Suman Wang,Michal Levin,Yunyu Shi,Dennis Kappei,Falk Butter +9 more
TL;DR: ZBTB10 is identified as the first TTGGGG-binding protein and direct binding via the two zinc fingers with affinity in the nanomolar range is demonstrated and established as a novel variant repeat binding protein at ALT telomeres.
Journal ArticleDOI
ERH facilitates microRNA maturation through the interaction with the N-terminus of DGCR8.
S. Chul Kwon,S. Chul Kwon,Harim Jang,Siyuan Shen,S. Chan Baek,Kijun Kim,Jihye Yang,Jeesoo Kim,Jong-Seo Kim,Suman Wang,Yunyu Shi,Fudong Li,V. Narry Kim +12 more
TL;DR: The study reveals a role of ERH in the miRNA biogenesis pathway and reveals that the ERH dimer may mediate ‘cluster assistance’ in which Microprocessor is loaded onto a poor substrate with help from a high-affinity substrate in the same cluster.
Journal ArticleDOI
Structural basis of the interaction between SETD2 methyltransferase and hnRNP L paralogs for governing co-transcriptional splicing.
Saikat Bhattacharya,Suman Wang,Divya Reddy,Siyuan Shen,Ying Zhang,Ning Zhang,Hua Li,Michael P. Washburn,Laurence Florens,Yunyu Shi,Jerry L. Workman,Fudong Li +11 more
TL;DR: In this article, the authors describe the mode of interaction between hnRNP L and LL with the methyltransferase SETD2 and demonstrate that for the interaction to occur, a leucine pair within a highly conserved stretch of SetD2 insert their side chains in hydrophobic pockets formed by hnRN L RRM2.
Journal ArticleDOI
A full set of 8,4'-oxy-8'-phenylneolignan stereoisomers from Sophora tonkinensis and their absolute configurations by TDDFT.
Hao-Ke He,Xin Li,Shufeng Yang,Meng-Yin Tian,Qian Zhang,Jing Zhang,Qi Hou,Mingbao Lin,Suman Wang +8 more
TL;DR: In this article , a full set of 8,4'-oxy-8'-phenylneolignans with four chiral carbons were isolated from the roots and rhizomes of Sophora tonkinensis Gagnep, including 14 previously undescribed stereoisomers, along with 2 known leptolepisol D diastereomers.
Posted ContentDOI
Structural basis of the interaction between SETD2 methyltransferase and hnRNP L paralogs for governing co-transcriptional splicing
Saikat Bhattacharya,Suman Wang,Divya Reddy,Siyuan Shen,Ying Zhang,Ning Zhang,Hua Li,Michael P. Washburn,Laurence Florens,Yunyu Shi,Fudong Li,Jerry L. Workman +11 more
TL;DR: In this article, the authors describe the mode of interaction between hnRNP L and LL with the methyltransferase SETD2 and demonstrate that for the interaction to occur, a leucine pair within a highly conserved stretch of SetD2 insert their side chains in hydrophobic pockets formed by hnRN L RRM2.