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Sumio Sugano

Researcher at University of Tokyo

Publications -  394
Citations -  34789

Sumio Sugano is an academic researcher from University of Tokyo. The author has contributed to research in topics: Gene & Complementary DNA. The author has an hindex of 76, co-authored 393 publications receiving 31681 citations. Previous affiliations of Sumio Sugano include Tokyo Medical and Dental University & Rockefeller University.

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High-throughput classification of images of cells transfected with cDNA clones.

TL;DR: An automatic system that handles the transfection, incubation, acquisition of microscopic images of the cells, and the classification of forms there appearing in the images correctly classified proteins by their forms at a rate of 90% in feasibility studies is reported here.
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Restriction glycosylases: involvement of endonuclease activities in the restriction process.

TL;DR: The results support generalization of the concept of restriction–modification system to the idea of self-recognizing epigenetic system, which combines any epigenetic labeling and any DNA damaging, and point to diversity among the endonucleases.
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Identification of potential regulatory mutations using multi-omics analysis and haplotyping of lung adenocarcinoma cell lines.

TL;DR: 137 potential regulatory mutations affecting the transcriptional regulation of 146 RefSeq transcripts with at least 84 SNVs that create and/or disrupt potential transcription factor binding sites were identified and revealed 31 disruptions were presented in clinical lung adenocarcinoma samples and were associated with prognosis of patients.
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Molecular cloning and characterization of a gene expressed in mouse developing tongue, mDscr5 gene, a homolog of human DSCR5 (Down syndrome Critical Region gene 5).

TL;DR: DSCR5 may be the first candidate to elucidate the pathophysiology of tongue malformation observed in DS by combination of computational gene prediction and cDNA screening.