Sumio Sugano

TL;DR: It is reported that mice with a nervous system-specific deletion of Bmal1 (N-Bmal1−/− mice) had a severe deficit in entrainment of locomotor activity by periodic feeding, accompanied by reduced food intake and subsequent loss of body weight.

TL;DR: Mice vaccinated with a DNA vaccine consisting of 2000 pooled clones showed significantly prolonged survival after challenge infection and spleen cells of vaccinated mice produced augmented levels of IL-2 and IFN-gamma when incubated with the crude parasite antigens, indicating that cellular immunity plays an important role in the protection.

TL;DR: Novel molecular mechanisms of chemotherapy resistance by a comprehensive analysis of changes in gene expression profiles (GEPs) are identified in canine lymphoma at chemotherapy sensitive and chemotherapy resistant phases.

TL;DR: Xenograft examination in athymic nude mice demonstrated that TbetaRII-positive SW-13 cells reduced tumor-forming activity, and it was shown that Reconstructing the T betaRII can lead to reversion of the malignant phenotype of Tbeta RII-negative human adrenocortical carcinoma, which contains SW- 13 cells.

TL;DR: Mgat5-dependent glycosylation of proteins can modulate acquired immune responses, but it is not essential for the development of OVA-induced eosinophilic airway inflammation.