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Susan Kohlhaas
Researcher at Babraham Institute
Publications - 5
Citations - 1422
Susan Kohlhaas is an academic researcher from Babraham Institute. The author has contributed to research in topics: Cellular differentiation & Medicine. The author has an hindex of 3, co-authored 3 publications receiving 1301 citations.
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Journal ArticleDOI
microRNA-155 Regulates the Generation of Immunoglobulin Class-Switched Plasma Cells
Elena Vigorito,Kerry L. Perks,Cei Abreu-Goodger,Sam F Bunting,Zou Xiang,Susan Kohlhaas,Partha Pratim Das,Eric A. Miska,Antony Rodriguez,Allan Bradley,Kenneth G. C. Smith,Cristina Rada,Anton J. Enright,Kai-Michael Toellner,Ian C. M. MacLennan,Martin R Turner +15 more
TL;DR: The intrinsic requirement for miR-155 is shown in B cell responses to thymus-dependent and -independent antigens and implicate post-transcriptional regulation of gene expression for establishing the terminal differentiation program of B cells.
Journal ArticleDOI
Cutting Edge: The Foxp3 Target miR-155 Contributes to the Development of Regulatory T Cells
Susan Kohlhaas,Oliver A. Garden,Cheryl L. Scudamore,Martin R Turner,Klaus Okkenhaug,Elena Vigorito +5 more
TL;DR: It is reported that miR-155-deficient mice have reduced numbers of Tregs, both in the thymus and periphery, due to impaired development, and that additional miRNAs control Treg function.
Journal ArticleDOI
miR-155: an ancient regulator of the immune system
TL;DR: The role of miR‐155 in the regulation of lymphoid subsets at the cellular and molecular level in the context of recent progress in this field is summarized.
Journal ArticleDOI
RENEWAL: REpurposing study to find NEW compounds with Activity for Lewy body dementia—an international Delphi consensus
John T. O'Brien,Leonidas Chouliaras,Janet Sultana,John B. Taylor,Clive Ballard,Dag Aarsland,F. Blanco,B. W. Boeve,David J. Brooks,K. Ray Chaudhuri,Jeffrey L. Cummings,Howard Feldman,Leon Flicker,James E. Galvin,Donald G. Grosset,Manabu Ikeda,Susan Kohlhaas,B.. Auteur ou responsable intellectuel Lawlor,Afina W. Lemstra,Iracema Leroi,Elisabet Londos,James B. Leverenz,Simon Lewis,Ian G. McKeith,Roger G. Mills,Richard Oakley,J. Steven Richardson,Marwan N. Sabbagh,John Skidmore,Per Svennigsson,Pietro Tiraboschi,Daniel Weintraub,Zuzana Walker,Rosie Watson,Rimona S. Weil,Caroline H. Williams-Gray,Alison J. Yarnall +36 more
TL;DR: In this paper , the authors identified ambroxol as the top ranked agent for repurposing and identified a further six agents from the classes of tyrosine kinase inhibitors, GLP-1 receptor agonists, and angiotensin receptor blockers that were rated by the majority of expert panel as justifying a clinical trial.
Journal ArticleDOI
The dementia research career pipeline: Gender disparities in publication authorships and grant funding outcomes at different career stages
TL;DR: The results confirm that female researchers leave dementia academic research at higher rates than men, before transitioning into senior positions, and offer interventions ARUK can implement in its application and evaluation process to address those disparities.