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Susan L. Morris-Natschke

Researcher at University of North Carolina at Chapel Hill

Publications -  287
Citations -  9762

Susan L. Morris-Natschke is an academic researcher from University of North Carolina at Chapel Hill. The author has contributed to research in topics: Cytotoxicity & Camptothecin. The author has an hindex of 48, co-authored 284 publications receiving 8331 citations. Previous affiliations of Susan L. Morris-Natschke include China Medical University (Taiwan) & Shandong University.

Papers
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Journal ArticleDOI

Recent Advances in the Discovery and Development of Topoisomerase Inhibitors as Antitumor Agents

Hui Kang Wang, +2 more
- 07 Oct 1997 - 
Journal ArticleDOI

Kleinhospitine E and Cycloartane Triterpenoids from Kleinhovia hospita

Abdul Rahim, +10 more
- 16 Jul 2018 - 
TL;DR: Biological evaluation revealed that compounds 4 and 9 exhibited more potent antiproliferative activities against a multidrug-resistant tumor cell line compared with its parent chemosensitive cell line, and compound 6 exhibited submicromolar anti-HIV activity.
Journal ArticleDOI

Anti-AIDS agents. Part 62: anti-HIV activity of 2'-substituted 4-methyl-3',4'-di-O-(-)-camphanoyl-(+)-cis-khellactone (4-methyl DCK) analogs.

Qian Zhang, +7 more
- 06 Dec 2004 - 
TL;DR: The bioassay results indicated that the 2'-substituents had a strong effect on the anti-HIV activity, and gem-dimethyl substitution at the 2-position was greatly preferable to larger alkyl substituents or hydrogen atoms.
Patent

Compositions and Methods for Double-Targeting Virus Infections and Targeting Cancer Cells

Louis S. Kucera, +4 more
TL;DR: In this article, the authors proposed a double-targeting approach for the treatment of a virus infection in a mammal by double targeting the virus at more than one stage of the virus life cycle and thereby inhibiting virus replication.
Journal ArticleDOI

Synthesis and bioactivity of 4,10-dimethyl-pyridino[2,3-h]quinolin-2(1H)-one-9-carboxylic acid and its esters.

Qian Zhang, +8 more
- 01 Mar 2003 - 
TL;DR: The 9-carboxyl (1s)-endo-(-)-borneol ester showed marginal cytotoxic activity in CAK1-1, HOS, KB, and HCT-8 cells, and its esters were evaluated in cytotoxicity and anti-HIV assays.