S
Susan L. Morris-Natschke
Researcher at University of North Carolina at Chapel Hill
Publications - 287
Citations - 9762
Susan L. Morris-Natschke is an academic researcher from University of North Carolina at Chapel Hill. The author has contributed to research in topics: Cytotoxicity & Camptothecin. The author has an hindex of 48, co-authored 284 publications receiving 8331 citations. Previous affiliations of Susan L. Morris-Natschke include China Medical University (Taiwan) & Shandong University.
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Book ChapterDOI
Asymmetric Synthesis of Chiral Tertiary Alcohols in High Enantiomeric Excess
Ernest L. Eliel,Jorma Koskimies,Bruno Lohri,W. Jack Frazee,Susan L. Morris-Natschke,Joseph E. Lynch,Kenso Soai +6 more
Journal ArticleDOI
Optimization of the antiviral potency and lipophilicity of halogenated 2,6-diarylpyridinamines as a novel class of HIV-1 NNRTIS.
Zhi Yuan Wu,Na Liu,Bingjie Qin,Li Huang,Fei Yu,Keduo Qian,Susan L. Morris-Natschke,Shibo Jiang,Shibo Jiang,Chin Ho Chen,Kuo Hsiung Lee,Kuo Hsiung Lee,Lan Xie +12 more
TL;DR: Two new halogenated diarylpyridinamine analogues modified at the phenoxy C‐ring displayed low‐nanomolar antiviral potency against wild‐type and drug‐resistant viral strains bearing the E138K or K101E mutations, which are associated with resistance to rilvipirine.
Journal ArticleDOI
Inhibition of human immunodeficiency virus envelope glycoprotein-mediated cell fusion by synthetic phospholipid analogs
Journal ArticleDOI
Talarolactone A, an Isocoumarin Derivative Fused with Dihydrothiophene with Selective Antimigratory Activity from the Endolichenic Fungus Talaromyces sp.
Wei-Hua Yuan,Meng-Ting Teng,Yang-Fang Yun,Nan Jiang,Lin Ma,Shan-Shan Sun,Bo Yuan,Jian Tang,Qian-Yu Wu,Qian Li,Peng Zhang,Susan L. Morris-Natschke,Kuo Hsiung Lee,Kuo Hsiung Lee +13 more
TL;DR: Compound 1 showed selective antimigratory activity in a wound-healing assay without appreciable cytotoxic activity and a plausible biosynthetic pathway of 1 was further proposed.
Journal ArticleDOI
Salvisertin A, a New Hexacyclic Triterpenoid, and Other Bioactive Terpenes from Salvia deserta Root
Yin Ru Wang,Yun Yu,Shu Ming Li,Wei Liu,Wei Liu,Wei Li,Susan L. Morris-Natschke,Masuo Goto,Kuo Hsiung Lee,Kuo Hsiung Lee,Xue Feng Huang,Xue Feng Huang +11 more
TL;DR: Using various chromatographic methods, a new hexacyclic triterpenoid was isolated from the roots of Salvia deserta and showed cytotoxic potency against A549, MDA‐MB‐231, KB, KB‐VIN, and MCF7 cell lines with IC50 values ranging from 6.5 to 10.2 μm.