S
Susan L. Morris-Natschke
Researcher at University of North Carolina at Chapel Hill
Publications - 287
Citations - 9762
Susan L. Morris-Natschke is an academic researcher from University of North Carolina at Chapel Hill. The author has contributed to research in topics: Cytotoxicity & Camptothecin. The author has an hindex of 48, co-authored 284 publications receiving 8331 citations. Previous affiliations of Susan L. Morris-Natschke include China Medical University (Taiwan) & Shandong University.
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Journal ArticleDOI
Anti-aids agents. Part 58: synthesis and anti-HIV activity of 1-thia-di-O-(-)-camphanoyl-(+)-cis-khellactone(1-thia-DCK) analogues
Peng Xia,Zhi Jian Yin,Ying Chen,Qian Zhang,Beina Zhang,Yi Xia,Zheng Yu Yang,Nicole Kilgore,Carl T. Wild,Susan L. Morris-Natschke,Kuo Hsiung Lee +10 more
TL;DR: The bioassay results indicated that thia-DCK analogues merit attention as potential HIV-1 inhibitors.
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Chemical Structures and Biological Activities of Limonoids from the Genus Swietenia (Meliaceae).
Yun Peng Sun,Wen Fang Jin,Yong Yue Wang,Gang Wang,Susan L. Morris-Natschke,Jin-Song Liu,Guo Kai Wang,Guo Kai Wang,Kuo Hsiung Lee,Kuo Hsiung Lee +9 more
TL;DR: This paper will give a comprehensive overview of the recent phytochemical and pharmacological research on the terpenes from Swietenia plants and encourage further drug discovery research.
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Secondary metabolites from the Chinese liverwort Cephaloziella kiaeri.
Rui Juan Li,Rong Xiu Zhu,Yao Yao Li,Jin Chuan Zhou,Jiao Zhen Zhang,Song Wang,Jian Ping Ye,Yue-Hu Wang,Susan L. Morris-Natschke,Kuo Hsiung Lee,Hong Xiang Lou +10 more
TL;DR: Sixteen new clerodane diterpenoids, cephaloziellins A-P (1-16), and two known analogues (17 and 18) were isolated from an EtOH extract of the Chinese liverwort, and the structures of 5, 9, and 15 were confirmed by single-crystal X-ray diffraction analyses.
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Membrane-Interactive Phospholipids Inhibit HIV Type 1-Induced Cell Fusion and Surface gp160/gp120 Binding to Monoclonal Antibody
Lisa Krugner-Higby,David C. Goff,Terri Edwards,Nathan Iyer,Jay Neufeld,Timothy E. Kute,Susan L. Morris-Natschke,Khalid S. Ishaq,Claude Piantadosi,Louis S. Kucera +9 more
TL;DR: Results suggest that anti-HIV-1 activity of PL compounds involves alteration of cell surface membranes and viral envelopes.
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Synthesis, antitumor activity, and mechanism of action of 6-acrylic phenethyl ester-2-pyranone derivatives
Sai Fang,Lei Chen,Miao Yu,Bao Cheng,Yongsheng Lin,Susan L. Morris-Natschke,Kuo Hsiung Lee,Kuo Hsiung Lee,Qiong Gu,Qiong Gu,Jun Xu +10 more
TL;DR: Compound is a promising compound as an antitumor agent that showed good ADMET properties with good absorption, low hepatotoxicity, and good solubility, and thus, could easily be bound to carrier proteins, without inhibition of CYP2D6.