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Susan L. Morris-Natschke

Researcher at University of North Carolina at Chapel Hill

Publications -  287
Citations -  9762

Susan L. Morris-Natschke is an academic researcher from University of North Carolina at Chapel Hill. The author has contributed to research in topics: Cytotoxicity & Camptothecin. The author has an hindex of 48, co-authored 284 publications receiving 8331 citations. Previous affiliations of Susan L. Morris-Natschke include China Medical University (Taiwan) & Shandong University.

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Lipid analogs for treating viral infections

Louis S. Kucera, +2 more
TL;DR: In this paper, a method of treating viral infections, and in particular HIV-1, hepatitis B virus, and herpesviruses, is disclosed, which consists in administering to a subject in need of such treatment an infection-combating amount of a phospholipid or phospholippid derivative.
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Carolignans from the Aerial Parts of Euphorbia sikkimensis and Their Anti-HIV Activity.

Cheng Jiang, +10 more
- 12 Jan 2016 - 
TL;DR: Seven new carolignans, including two pairs of enantiomers (±)-erythro-7'-methylcarolignan E (1a/1b) and (±-threo-7-methylcarols E (2a/2b), plus four known lignans and six polyphenols were isolated from the aerial parts of Euphorbia sikkimensis for anti-HIV effects.
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Eremophilane sesquiterpenes from Ligularia macrophylla.

Qi Wang, +5 more
- 01 Aug 2007 - 
TL;DR: New eremophilane sesquiterpenes isolated from the roots and rhizomes of Ligularia macrophylla showed only very weak cytotoxicity against human lung carcinoma and human breast adenocarcinoma.
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Anti-AIDS agents 73: structure-activity relationship study and asymmetric synthesis of 3-O-monomethylsuccinyl-betulinic acid derivatives.

Keduo Qian, +7 more
- 01 Dec 2007 - 
TL;DR: 3-O-3'(or 2')-Methylsuccinyl-betulinic acid derivatives were separated by using recycle HPLC and exhibited potent anti-HIV activity, comparable to the data for bevirimat (DSB, PA-457), a current clinical trials drug that was also derived from betulinic Acid.
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Xanthohumol isolated from Humulus lupulus prevents thrombosis without increased bleeding risk by inhibiting platelet activation and mtDNA release.

Guang Xin, +19 more
- 01 Jul 2017 - 
TL;DR: Xanthohumol exemplifies a promising new class of antiplatelet agents that are highly effective at inhibiting platelet activation by decreasing ROS accumulation and platelet mtDNA release without incurring a bleeding risk.