Susan Nehzati

TL;DR: It is shown that brain iron tends to decrease with increasing age and disease duration of MS patients; reactive astrocytes organized in large astrogliotic areas in a subset of smoldering and inactive plaques accumulate iron and safely store it in ferritin and upon degeneration of iron-loaded microglia/macrophages may form an additional protective barrier that may prevent iron-induced oxidative damage.

TL;DR: Micro X-ray absorption spectra support the hypothesis that the co-localized deposits are most likely comprised of highly insoluble mixed chalcogenide HgSxSe(1-x) where x is 0.4-0.9, probably with the cubic zincblende structure.

TL;DR: Using newly-available methods to re-examine the cerebellum of historic Cat 717, synchrotron high energy resolution fluorescence detection-X-ray absorption spectroscopy revealed sulfur-bound organometallic mercury with a minor β-HgS phase in factory effluent.

TL;DR: It is found that the organic forms of selenium tested show considerably more toxicity than inorganic forms (selenite and selenate), and that this appears to be correlated with the level of bioaccumulation.

TL;DR: The results demonstrate for the first time the direct and complete binding of the metal atom of the inhibitors to the selenium atom in TrxR1 for both methylmercury and auranofin, indicating that TrXR1 inhibition indeed can be attributed to such direct metal-selenium binding.