S
Susanne Rössner
Researcher at University of Erlangen-Nuremberg
Publications - 15
Citations - 4203
Susanne Rössner is an academic researcher from University of Erlangen-Nuremberg. The author has contributed to research in topics: Dendritic cell & T cell. The author has an hindex of 12, co-authored 15 publications receiving 4041 citations.
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Journal ArticleDOI
12/15-lipoxygenase–mediated enzymatic lipid oxidation regulates DC maturation and function
Tobias Rothe,Florian Gruber,Stefan Uderhardt,Natacha Ipseiz,Susanne Rössner,Olga Oskolkova,Stephan Blüml,Norbert Leitinger,Wolfgang Bicker,Valery N. Bochkov,Masayuki Yamamoto,Alexander Steinkasserer,Georg Schett,Elisabeth Zinser,Gerhard Krönke +14 more
TL;DR: It is determined that 12/15-lipoxygenase-meditated (12/ 15-LO-mediated) enzymatic lipid oxidation regulates DC activation and fine-tunes consecutive T cell responses and implicate enzymatics lipid oxidation in shaping the adaptive immune response.
Journal ArticleDOI
TLR9 cooperates with TLR4 to increase IL-12 release by murine dendritic cells.
Gabi Theiner,Susanne Rössner,Alexander H. Dalpke,Konrad A. Bode,Thomas G. Berger,André Gessner,Manfred B. Lutz,Manfred B. Lutz +7 more
TL;DR: It is shown that TLR4 and TLR9 can cooperate to increase selectively IL-12 production by DC, and the stimulatory effect could be further enhanced by addition of IFN-gamma but not anti-CD40 antibodies.
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Formation and kinetics of MHC class I-ovalbumin peptide complexes on immature and mature murine dendritic cells.
TL;DR: Pulse-chase experiments revealed a constant half-life of peptide/Kb complexes independent of preceding DC stimulation or their maturation stage, which might have important implications for the clinical application of peptides-pulsed DC in tumor immunotherapy.
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Topical Application of Soluble CD83 Induces IDO-Mediated Immune Modulation, Increases Foxp3+ T Cells, and Prolongs Allogeneic Corneal Graft Survival
Felix Bock,Susanne Rössner,Jasmine Onderka,Matthias Lechmann,Maria Teresa Pallotta,Francesca Fallarino,Louis Boon,Charles A. Nicolette,Mark A. DeBenedette,Irina Y. Tcherepanova,Ursula Grohmann,Alexander Steinkasserer,Claus Cursiefen,Elisabeth Zinser +13 more
TL;DR: Interestingly, sCD83 was able to prolong graft survival after systemic application as well as after topical application, which is therapeutically more relevant, and open new treatment avenues for local immune modulation after organ and tissue transplantation.
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Factors influencing the generation of murine dendritic cells from bone marrow: The special role of fetal calf serum
Manfred B. Lutz,Susanne Rössner +1 more
TL;DR: The factors that have an impact on the generation of BM-DC, including criteria regarding the mice, but also technical parameters and the different growth factors are reviewed.