K
Kimihiko Kaneko
Researcher at Tohoku University
Publications - 71
Citations - 1698
Kimihiko Kaneko is an academic researcher from Tohoku University. The author has contributed to research in topics: Myelin oligodendrocyte glycoprotein & Optic neuritis. The author has an hindex of 16, co-authored 60 publications receiving 1054 citations. Previous affiliations of Kimihiko Kaneko include Tohoku Pharmaceutical University & Fukushima Medical University.
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Journal ArticleDOI
MOG antibody–positive, benign, unilateral, cerebral cortical encephalitis with epilepsy
Ryo Ogawa,Ichiro Nakashima,Toshiyuki Takahashi,Kimihiko Kaneko,Tetsuya Akaishi,Yoshiki Takai,Douglas Kazutoshi Sato,Shuhei Nishiyama,Tatsuro Misu,Hiroshi Kuroda,Masashi Aoki,Kazuo Fujihara +11 more
TL;DR: The features of adult patients with benign, unilateral cerebral cortical encephalitis positive for the myelin oligodendrocyte glycoprotein (MOG) antibody mean the pathology may be autoimmune, although the findings differ from MOG antibody–associated demyelination and Rasmussen and other known immune-mediated encephalitides.
Journal ArticleDOI
Myelin oligodendrocyte glycoprotein antibody-associated disease: an immunopathological study.
Yoshiki Takai,Tatsuro Misu,Kimihiko Kaneko,Norio Chihara,Koichi Narikawa,Satoko Tsuchida,Hiroya Nishida,Takashi Komori,Morinobu Seki,Teppei Komatsu,Kiyotaka Nakamagoe,Toshimasa Ikeda,Mari Yoshida,Toshiyuki Takahashi,Hirohiko Ono,Shuhei Nishiyama,Hiroshi Kuroda,Ichiro Nakashima,Hiroyoshi Suzuki,Monika Bradl,Hans Lassmann,Kazuo Fujihara,Kazuo Fujihara,Masashi Aoki +23 more
TL;DR: This study suggests that ADEM-like perivenous inflammatory demyelination with MOG-dominant myelin loss is a characteristic finding of MOG antibody-associated disease regardless of whether the diagnostic criteria of ADEM are met.
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MRI and retinal abnormalities in isolated optic neuritis with myelin oligodendrocyte glycoprotein and aquaporin-4 antibodies: a comparative study.
Tetsuya Akaishi,Douglas Kazutoshi Sato,Ichiro Nakashima,Takayuki Takeshita,Toshiyuki Takahashi,Hiroshi Doi,Kazuhiro Kurosawa,Kimihiko Kaneko,Hiroshi Kuroda,Shuhei Nishiyama,Tatsuro Misu,Toru Nakazawa,Kazuo Fujihara,Masashi Aoki +13 more
TL;DR: The diagnostic utility of the anti-MOG assay was evaluated and the MRI and OCT findings of anti- MOG+ and anti-AQP4+ patients with isolated ON were compared.
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Treatment of MOG-IgG-associated disorder with rituximab: An international study of 121 patients
Daniel Whittam,Daniel Whittam,Alvaro Cobo-Calvo,A. Sebastian Lopez-Chiriboga,Santiago Pardo,Matthew Gornall,Silvia Cicconi,Alexander U. Brandt,Klaus Berek,Thomas Berger,Ilijas Jelcic,Grace Y. Gombolay,Luana Micheli Oliveira,Dagoberto Callegaro,Kimihiko Kaneko,Tatsuro Misu,Marco Capobianco,Emily Gibbons,Venkatraman Karthikeayan,Bruno Brochet,Bertrand Audoin,Guillaume Mathey,David Laplaud,Eric Thouvenot,Mikael Cohen,Ayman Tourbah,Elisabeth Maillart,Jonathan Ciron,Romain Deschamps,Damien Biotti,Kevin Rostasy,Rinze F. Neuteboom,Cheryl Hemingway,Rob Forsyth,Marcelo Matiello,Stewart Webb,David M. Hunt,Katy Murray,Yael Hacohen,Ming K. Lim,M. Isabel Leite,Jacqueline Palace,Tom Solomon,Andreas Lutterotti,Kazuo Fujihara,Ichiro Nakashima,Jeffrey Bennett,Lekha Pandit,Tanuja Chitnis,Brian G. Weinshenker,Brigitte Wildemann,Douglas Kazutoshi Sato,Su Hyun Kim,Saif Huda,Ho Jin Kim,Markus Reindl,Michael J. Levy,Sven Jarius,Silvia Tenembaum,Friedemann Paul,Sean J. Pittock,Romain Marignier,Anu Jacob,Anu Jacob,Anu Jacob +64 more
TL;DR: RTX reduced relapse rates in MOGAD, however, many patients continued to relapse despite apparent B-cell depletion, and Prospective controlled studies are needed to validate these results.
Journal ArticleDOI
Bilateral frontal cortex encephalitis and paraparesis in a patient with anti-MOG antibodies
Juichi Fujimori,Yoshiki Takai,Ichiro Nakashima,Douglas Kazutoshi Sato,Toshiyuki Takahashi,Kimihiko Kaneko,Shuhei Nishiyama,Mika Watanabe,Hiroaki Tanji,Michiko Kobayashi,Tatsuro Misu,Masashi Aoki,Kazuo Fujihara +12 more
TL;DR: Interestingly, the initial paraparesis evolved into an acute disseminated encephalomyelitis (ADEM)-like illness and optic neuritis, and the patient was found to be positive for anti-myelin oligodendrocyte glycoprotein (MOG) antibodies.