T
Takanori Morikawa
Researcher at Tohoku University
Publications - 110
Citations - 1424
Takanori Morikawa is an academic researcher from Tohoku University. The author has contributed to research in topics: Pancreatic cancer & Medicine. The author has an hindex of 18, co-authored 96 publications receiving 1097 citations.
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Journal ArticleDOI
Intraductal tubulopapillary neoplasms of the pancreas distinct from pancreatic intraepithelial neoplasia and intraductal papillary mucinous neoplasms.
Hiroshi Yamaguchi,Michio Shimizu,Shinichi Ban,Isamu Koyama,Takashi Hatori,Izumi Fujita,Masakazu Yamamoto,Shunji Kawamura,Makio Kobayashi,Kazuyuki Ishida,Takanori Morikawa,Fuyuhiko Motoi,Michiaki Unno,Atsushi Kanno,Kennichi Satoh,Tooru Shimosegawa,Hideki Orikasa,Tomoo Watanabe,Kazuhiko Nishimura,Yoshiro Ebihara,Naoto Koike,Toru Furukawa +21 more
TL;DR: ITPNs can be considered to represent a new disease entity encompassing intraductal tubular carcinoma as a morphologic variant as well as several features of acinar cell carcinoma, except for the tubulopapillary growth pattern.
Journal ArticleDOI
Multicenter comparative study of laparoscopic and open distal pancreatectomy using propensity score-matching.
Masafumi Nakamura,Go Wakabayashi,Yoshihiro Miyasaka,Masao Tanaka,Takanori Morikawa,Michiaki Unno,Hiroshi Tajima,Yusuke Kumamoto,Sohei Satoi,Masanori Kwon,Hirochika Toyama,Yonson Ku,Hideyuki Yoshitomi,Satoshi Nara,Kazuaki Shimada,Takahide Yokoyama,Shinichi Miyagawa,Yoichi Toyama,Katsuhiko Yanaga,Tsutomu Fujii,Yasuhiro Kodera,Yasuyuki Tomiyama,Hiroaki Miyata,Takeshi Takahara,Toru Beppu,Hiroki Yamaue,Masaru Miyazaki,Tadahiro Takada +27 more
TL;DR: This study aimed to compare laparoscopic and open distal pancreatectomy using propensity score‐matching and found no differences between the two methods.
Journal ArticleDOI
Major hepatectomy for perihilar cholangiocarcinoma.
Michiaki Unno,Yu Katayose,Toshiki Rikiyama,Hiroshi Yoshida,Kuniharu Yamamoto,Takanori Morikawa,Hiroki Hayashi,Fuyuhiko Motoi,Shinichi Egawa +8 more
TL;DR: Major hepatectomy for perihilar cholangiocarcinoma was acceptable and showed satisfactory outcomes and the surgeon should aim for complete resection of the tumor with negative margins for long-term survival in these patients.
Journal ArticleDOI
Somatic mutations in PIK3CA and activation of AKT in intraductal tubulopapillary neoplasms of the pancreas.
Hiroshi Yamaguchi,Yuko Kuboki,Takashi Hatori,Masakazu Yamamoto,Keiko Shiratori,Shunji Kawamura,Makio Kobayashi,Michio Shimizu,Shinichi Ban,Isamu Koyama,Morihiro Higashi,Nobuhiro Shin,Kazuyuki Ishida,Takanori Morikawa,Fuyuhiko Motoi,Michiaki Unno,Atsushi Kanno,Kennichi Satoh,Tooru Shimosegawa,Hideki Orikasa,Tomoo Watanabe,Kazuhiko Nishimura,Youji Harada,Toru Furukawa +23 more
TL;DR: Results indicate that activation of the phosphatidylinositol 3-kinase pathway may play a crucial role in ITPNs but not in IPMNs, and the activated phosphorylated AKT pathway may be a potential target for molecular diagnosis and therapy of I TPNs.
Journal ArticleDOI
Pancreatic intraductal tubulopapillary neoplasm is genetically distinct from intraductal papillary mucinous neoplasm and ductal adenocarcinoma
Olca Basturk,Michael F. Berger,Hiroshi Yamaguchi,Volkan Adsay,Gokce Askan,Umesh Bhanot,Ahmet Zehir,Fátima Carneiro,Seung-Mo Hong,Giuseppe Zamboni,Esra Dikoglu,Vaidehi Jobanputra,Kazimierz O. Wrzeszczynski,Serdar Balci,Peter J. Allen,Naoki Ikari,Shoko Takeuchi,Hiroyuki Akagawa,Atsushi Kanno,Tooru Shimosegawa,Takanori Morikawa,Fuyuhiko Motoi,Michiaki Unno,Ryota Higuchi,Masakazu Yamamoto,Kyoko Shimizu,Toru Furukawa,David S. Klimstra +27 more
TL;DR: The results suggest that intraductal tubulopapillary neoplasm has distinguishing genetic characteristics and some of these mutated genes are potentially targetable.