Takashi Okamoto

TL;DR: Cellular levels of thioredoxin appear to limit sensitivity to various superoxide-generating anticancer drugs in cancer cells, by being established in several human bladder and prostatic cancer cell lines resistant to cis-diamminedichloroplatinum(II) (cisplatin).

TL;DR: Using immunohistochemical staining anti-ADF antibody, the enhancement of ADF/TRX expression on primary culture of human keratinocytes was demonstrated, 12 h after 20 mJ/cm2 UVB irradiation, and the augmentation of AD fusions was observed 6 h after treatment of H2O2.

TL;DR: Evidence is presented that the local environment in the rheumatic joint contributes to increased TRX production and it is proposed that increased expression of TRX contributes to the disease activity in RA.

TL;DR: It is demonstrated that LA has a more potent activity in inhibiting NF‐κB‐mediated gene expression in THP‐1 cells that have been stably transfected with a plasmid bearing a hygromycin B resistance gene under the control of HIV‐1 long terminal repeat (LTR) promoter.

TL;DR: It is concluded that AIDS‐KS cells produce a factor(s) that promotes VHP, and this factor could be VEGF, and the production of V EGF was demonstrated in freshAIDS‐KS tissue as well as in cultured AIDS‐ KS cells, while control cells were negative for VEGf production.