T
Tammo Diercks
Researcher at Technische Universität München
Publications - 54
Citations - 1528
Tammo Diercks is an academic researcher from Technische Universität München. The author has contributed to research in topics: Nuclear magnetic resonance spectroscopy & Glycan. The author has an hindex of 20, co-authored 50 publications receiving 1211 citations.
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Journal ArticleDOI
The Redox Potential of Selenocystine in Unconstrained Cyclic Peptides
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Applications of NMR in drug discovery
TL;DR: Its unmatched screening sensitivity, combined with the abundance of available information on the structure and nature of molecular binding, justifies the growing interest in this dynamically expanding NMR application.
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The solution structure and dynamics of human neutrophil gelatinase-associated lipocalin.
Murray Coles,Tammo Diercks,Bernd Muehlenweg,Stefan Bartsch,Volker Zölzer,Harald Tschesche,Horst Kessler +6 more
TL;DR: The structure provides a detailed model of the ligand-binding site and has led to the proposal of a site for pro-MMP-9 association, which has allowed us to investigate a mechanism by which a cell-surface receptor might distinguish between apo and holo-HNGAL through conformational changes at the open end of the barrel.
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The solution structure of VAT-N reveals a 'missing link' in the evolution of complex enzymes from a simple betaalphabetabeta element.
Murray Coles,Tammo Diercks,J. Liermann,Adriane Gröger,Beate Rockel,Wolfgang Baumeister,K.K. Koretke,Andrei N. Lupas,Jürgen Peters,Horst Kessler +9 more
TL;DR: The results suggest that VAT-N is a precursor of the aspartic proteinases that has acquired peptide-binding activity while remaining proteolytically incompetent.
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An efficient strategy for assignment of cross-peaks in 3D heteronuclear NOESY experiments
TL;DR: Two 3D-NOESY spectra are reported which, in concert with other commonly used spectra, provide a convenient strategy for NOE assignment and exploit the extra dispersion of the heteronucleus and considerably simplifying assignment.