T
Tania H. Watts
Researcher at University of Toronto
Publications - 150
Citations - 11082
Tania H. Watts is an academic researcher from University of Toronto. The author has contributed to research in topics: Cytotoxic T cell & T cell. The author has an hindex of 51, co-authored 139 publications receiving 10289 citations. Previous affiliations of Tania H. Watts include Stanford University.
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Tnf/tnfr family members in costimulation of t cell responses
TL;DR: This review focuses on CD27, 4-1BB, OX40, HVEM, CD30, and GITR, all of which can have costimulatory effects on T cells, and shows promise for several therapeutic applications, including cancer, infectious disease, transplantation, and autoimmunity.
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Supported planar membranes in studies of cell-cell recognition in the immune system.
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The B7 family member B7-H3 preferentially down-regulates T helper type 1-mediated immune responses
Woong-Kyung Suh,Beata U. Gajewska,Hitoshi Okada,Matthew A. Gronski,Edward M. Bertram,Wojciech Dawicki,Gordon S. Duncan,Jacob Bukczynski,Suzanne Plyte,Andrew E. H. Elia,Andrew Wakeham,Annick Itie,Stephen Chung,Joan da Costa,Sudha Arya,Tom Horan,Pauline Campbell,Kevin Gaida,Pamela S. Ohashi,Tania H. Watts,Steven Kiyoshi Yoshinaga,Mark R. Bray,Manel Jordana,Tak W. Mak +23 more
TL;DR: B7-H3 is a negative regulator that preferentially affects TH1 responses and develops experimental autoimmune encephalomyelitis several days earlier than their wild-type littermates, and accumulated higher concentrations of autoantibodies to DNA.
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Dendritic cell-induced autoimmune heart failure requires cooperation between adaptive and innate immunity.
Urs Eriksson,Romeo Ricci,Lukas Hunziker,Michael O. Kurrer,Gavin Y. Oudit,Tania H. Watts,Ivo Sonderegger,Kurt Bachmaier,Kurt Bachmaier,Manfred Kopf,Josef M. Penninger,Josef M. Penninger,Josef M. Penninger +12 more
TL;DR: DC–induced myocarditis provides a unifying theory as to how tissue damage and activation of TLRs during infection can induce autoimmunity, relapses and cardiomyopathy.
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T cell co-stimulatory molecules other than CD28
TL;DR: Recent developments suggest that additional co-stimulatory pathways have preferential effects at different stages of T cell activation, on different subsets of T cells or contribute to the development of different effector functions.