T
Taruna Madan
Researcher at National Institute for Research in Reproductive Health
Publications - 138
Citations - 4403
Taruna Madan is an academic researcher from National Institute for Research in Reproductive Health. The author has contributed to research in topics: Aspergillus fumigatus & Innate immune system. The author has an hindex of 31, co-authored 122 publications receiving 3973 citations. Previous affiliations of Taruna Madan include University of Delhi & Council of Scientific and Industrial Research.
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Journal ArticleDOI
Surfactant proteins SP-A and SP-D : Structure, function and receptors
Uday Kishore,Trevor J. Greenhough,Patrick Waters,Annette K. Shrive,Rohit Ghai,Mohammad F. Kamran,Andrés López Bernal,Kenneth B.M. Reid,Taruna Madan,Trinad Chakraborty +9 more
TL;DR: In this article, the structural and functional aspects of SP-A and SP-D with emphasis on their roles in controlling pulmonary infection, allergy and inflammation are discussed, and a recently proposed model based on studies with the calreticulin-CD91 complex as a receptor for SP-a andSP-D in naive lungs which would help minimise the potential damage that continual low level exposure to pathogens, allergens and apoptosis can cause.
Journal ArticleDOI
Binding of pulmonary surfactant proteins A and D to Aspergillus fumigatus conidia enhances phagocytosis and killing by human neutrophils and alveolar macrophages.
TL;DR: Findings indicate that SP-A and SP-D may have an important immunological role in the early antifungal defense responses in the lung, through inhibiting infectivity of conidia by agglutination and by enhancing uptake and killing of A. fumigatus by phagocytic cells.
Journal ArticleDOI
Genetic landscape of the people of India: A canvas for disease gene exploration
Samir K. Brahmachari,Partha P. Majumder,Mitali Mukerji,Saman Habib,Debasis Dash,Kunal Ray,Samira Bahl,Lalji Singh,Abhay Sharma,Susanta Roychoudhury,Giriraj R. Chandak,Kumarasamy Thangaraj,Devendra Parmar,Shantanu Sengupta,Dwaipayan Bharadwaj,Srikanta Kumar Rath,Jagmohan Singh,Ganga Nath Jha,Komal Virdi,V. R. Rao,Swapnil Sinha,Ashok K. Singh,Amit Kumar Mitra,Shrawan K. Mishra,Qadar Pasha,Sridhar Sivasubbu,Rajesh Pandey,Aradhita Baral,Prashant Singh,Amitabh Sharma,Jitender Kumar,Tsering Stobdan,Yasha Bhasin,Chitra Chauhan,Ashiq Hussain,Elyanambi Sundaramoorthy,Suchita Singh,Arun Bandyopadhyay,Krishanu Dasgupta,A. K. Reddy,Charles J. Spurgeon,M. Mohd Idris,Vinay K. Khanna,Alok Dhawan,Mohini Anand,Ravi Shankar,R. S. Bharti,Madhu Singh,Arvind P. Singh,Anwar J. Khan,Parag P. Shah,A. B. Pant,Rupinder Kaur,Kamlesh Bisht,Ashok Kumar,Victor Rajamanickam,Eugene Wilson,Antony Thangadurai,Pankaj Jha,Mahua Maulik,Neelam Makhija,Abdur Rahim,Sangeeta Sharma,Rupali Chopra,Pooja Rana,Manickam Chidambaram,Arindam Maitra,Ruchi Chawla,Suruchika Soni,Preeti Khurana,Mohamed Nadeem Khan,Sushanta Das Sutar,Amit Tuteja,K. Narayansamy,Rachna Shukla,S. Prakash,Swapna Mahurkar,K. Radha Mani,J. Hemavathi,Seema Bhaskar,Pankaj Khanna,G. S. Ramalakshmi,Shalini Mani Tripathi,Nikita Thakur,Balaram Ghosh,Ritushree Kukreti,Taruna Madan,Ranjana Verma,G. Sudheer,Anubha Mahajan,Sreenivas Chavali,Rubina Tabassum,Sandeep Grover,Meenal Gupta,Jyotsna Batra,Amrendra Kumar,Abdoulazim Nejatizadeh,Mudit Vaid,Swapan K Das,Shilpy Sharma,Mamta Sharma,Rajshekhar Chatterjee,Jinny A. Paul,Pragya Srivastava,Charu Rajput,Uma Mittal,Mridula Singh,Manoj Hariharan,S.K. Das,Keya Chaudhuri,Mainak Sengupta,Moulinath Acharya,Ashima Bhattacharyya,A Saha,Arindam Biswas,Moumita Chaki,Arnab Gupta,Saibal Mukherjee,Suddhasil Mookherjee,Ishita Chattopadhyay,Taraswi Banerjee,Meenakshi Chakravorty,Chaitali Misra,Gourish Monadal,Shiladitya Sengupta,Dipanjana Dutta De,Swati Bajaj,Ishani Deb,Arunava Banerjee,Rajdeep Chowdhury,Debalina Banerjee,Deepak Kumar,Sumit Ranjan Das,Shrish Tiwari,Anshu Bharadwaj,Ikhlak Ahmed,Sumera Parveen,Nivedita Singh,Dipayan Dasgupta,Siddharth Singh Bisht,Sangeeta Khanna,Rashmi Rajput,Biswaroop Ghosh,Naveen Kumar,Amit Kumar Chaurasia,James Kappukalayil Abraham,Amit Sinha,Vinod Scaria,Tavpritesh Sethi,A. Mandal,Arijit Mukhopadhyay +150 more
TL;DR: High levels of genetic divergence are observed between groups of populations that cluster largely on the basis of ethnicity and language in diverse populations of India.
Journal ArticleDOI
Surfactant proteins A and D protect mice against pulmonary hypersensitivity induced by Aspergillus fumigatus antigens and allergens
Taruna Madan,Uday Kishore,Mamta Singh,Peter Strong,Howard Clark,Ejaj M. Hussain,Kenneth B.M. Reid,P. Usha Sarma +7 more
TL;DR: Results clearly implicate pulmonary SP-A and SP-D in the modulation of allergic reactions.
Journal ArticleDOI
Lung surfactant proteins A and D can inhibit specific IgE binding to the allergens of Aspergillus fumigatus and block allergen‐induced histamine release from human basophils
Taruna Madan,Uday Kishore,Anand Shah,Paul Eggleton,Peter Strong,Jiu-Yao Wang,S. S. Aggrawal,P. U. Sarma,Kenneth B M Reid +8 more
TL;DR: The view that SP‐A and SP‐D play a protective role against airborne allergens is further supported by the demonstration of their ability to inhibit A. fumigatus allergen‐induced histamine release from allergic patients' basophils.