M
Madhu Singh
Researcher at Indian Institute of Toxicology Research
Publications - 9
Citations - 745
Madhu Singh is an academic researcher from Indian Institute of Toxicology Research. The author has contributed to research in topics: Genotype & Haplotype. The author has an hindex of 8, co-authored 9 publications receiving 697 citations. Previous affiliations of Madhu Singh include Institute of Genomics and Integrative Biology & Council of Scientific and Industrial Research.
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Journal ArticleDOI
Genetic landscape of the people of India: A canvas for disease gene exploration
Samir K. Brahmachari,Partha P. Majumder,Mitali Mukerji,Saman Habib,Debasis Dash,Kunal Ray,Samira Bahl,Lalji Singh,Abhay Sharma,Susanta Roychoudhury,Giriraj R. Chandak,Kumarasamy Thangaraj,Devendra Parmar,Shantanu Sengupta,Dwaipayan Bharadwaj,Srikanta Kumar Rath,Jagmohan Singh,Ganga Nath Jha,Komal Virdi,V. R. Rao,Swapnil Sinha,Ashok K. Singh,Amit Kumar Mitra,Shrawan K. Mishra,Qadar Pasha,Sridhar Sivasubbu,Rajesh Pandey,Aradhita Baral,Prashant Singh,Amitabh Sharma,Jitender Kumar,Tsering Stobdan,Yasha Bhasin,Chitra Chauhan,Ashiq Hussain,Elyanambi Sundaramoorthy,Suchita Singh,Arun Bandyopadhyay,Krishanu Dasgupta,A. K. Reddy,Charles J. Spurgeon,M. Mohd Idris,Vinay K. Khanna,Alok Dhawan,Mohini Anand,Ravi Shankar,R. S. Bharti,Madhu Singh,Arvind P. Singh,Anwar J. Khan,Parag P. Shah,A. B. Pant,Rupinder Kaur,Kamlesh Bisht,Ashok Kumar,Victor Rajamanickam,Eugene Wilson,Antony Thangadurai,Pankaj Jha,Mahua Maulik,Neelam Makhija,Abdur Rahim,Sangeeta Sharma,Rupali Chopra,Pooja Rana,Manickam Chidambaram,Arindam Maitra,Ruchi Chawla,Suruchika Soni,Preeti Khurana,Mohamed Nadeem Khan,Sushanta Das Sutar,Amit Tuteja,K. Narayansamy,Rachna Shukla,S. Prakash,Swapna Mahurkar,K. Radha Mani,J. Hemavathi,Seema Bhaskar,Pankaj Khanna,G. S. Ramalakshmi,Shalini Mani Tripathi,Nikita Thakur,Balaram Ghosh,Ritushree Kukreti,Taruna Madan,Ranjana Verma,G. Sudheer,Anubha Mahajan,Sreenivas Chavali,Rubina Tabassum,Sandeep Grover,Meenal Gupta,Jyotsna Batra,Amrendra Kumar,Abdoulazim Nejatizadeh,Mudit Vaid,Swapan K Das,Shilpy Sharma,Mamta Sharma,Rajshekhar Chatterjee,Jinny A. Paul,Pragya Srivastava,Charu Rajput,Uma Mittal,Mridula Singh,Manoj Hariharan,S.K. Das,Keya Chaudhuri,Mainak Sengupta,Moulinath Acharya,Ashima Bhattacharyya,A Saha,Arindam Biswas,Moumita Chaki,Arnab Gupta,Saibal Mukherjee,Suddhasil Mookherjee,Ishita Chattopadhyay,Taraswi Banerjee,Meenakshi Chakravorty,Chaitali Misra,Gourish Monadal,Shiladitya Sengupta,Dipanjana Dutta De,Swati Bajaj,Ishani Deb,Arunava Banerjee,Rajdeep Chowdhury,Debalina Banerjee,Deepak Kumar,Sumit Ranjan Das,Shrish Tiwari,Anshu Bharadwaj,Ikhlak Ahmed,Sumera Parveen,Nivedita Singh,Dipayan Dasgupta,Siddharth Singh Bisht,Sangeeta Khanna,Rashmi Rajput,Biswaroop Ghosh,Naveen Kumar,Amit Kumar Chaurasia,James Kappukalayil Abraham,Amit Sinha,Vinod Scaria,Tavpritesh Sethi,A. Mandal,Arijit Mukhopadhyay +150 more
TL;DR: High levels of genetic divergence are observed between groups of populations that cluster largely on the basis of ethnicity and language in diverse populations of India.
Journal ArticleDOI
The Indian Genome Variation database (IGVdb): a project overview
Samir K. Brahmachari,Lalji Singh,Abhay Sharma,Mitali Mukerji,Kunal Ray,Susanta Roychoudhury,Giriraj R. Chandak,Kumarasamy Thangaraj,Saman Habib,Devendra Parmar,Partha P. Majumder,Shantanu Sengupta,Dwaipayan Bharadwaj,Debasis Dash,Srikanta Kumar Rath,Ravi Shankar,Jagmohan Singh,Komal Virdi,Samira Bahl,V. R. Rao,Swapnil Sinha,Ashok K. Singh,Amit Kumar Mitra,Shrawan K. Mishra,B. R. K. Shukla,Qadar Pasha,Souvik Maiti,Amitabh Sharma,Jitender Kumar,Aarif Ahsan,Tsering Stobdan,Chitra Chauhan,Shivali Malhotra,Ajay Vidhani,S. Siva,Aradhita Baral,Rajesh Pandey,Ravishankar Roy,Mridula Singh,Suchita Singh,Nitin Maurya,Arun Bandyopadhyay,Ganga Nath Jha,Somnath Dutta,Gautam Ghosh,Tufan Naiya,Manoj Jain,J. P. Srivatava,J. R. Gupta,Vinay Khanna,Alok Dhawan,Mohini Anand,R. S. Bharti,Madhu Singh,Arvind P. Singh,Anwar J. Khan,Kamlesh Bisht,Ashok Kumar,Balaram Ghosh,Swapan K Das,Taruna Madan,Ranjana Verma,Uma Mittal,Anubha Mahajan,Sreenivas Chavali,Rubina Tabassum,Vijaya Banerjee,Jyotsna Batra,Rana Nagarkatti,Shilpy Sharma,Mamta Sharma,Rajshekhar Chatterjee,Jinny A. Paul,Pragya Srivastava,Rupali Chopra,Ankur Saxena,Charu Rajput,Prashant Singh,Mudit Vaid,S.K. Das,Keya Chaudhuri,Rukhsana Chowdhury,Arijit Mukhopadhyay,Moulinath Acharya,Ashima Bhattacharyya,A Saha,Arindam Biswas,Moumita Chaki,Arnab Gupta,Saibal Mukherjee,Suddhasil Mookherjee,Ishita Chattopadhyay,Taraswi Banerjee,Meenakshi Chakravorty,Chaitali Misra,Gourish Monadal,Shiladitya Sengupta,Ishani Deb,Arunava Banerjee +98 more
TL;DR: The Indian Genome Variation (IGV) consortium as discussed by the authors is the first large-scale comprehensive study of the structure of the Indian population with wide-reaching implications, which aims to provide data on validated SNPs and repeats, both novel and reported, along with gene duplications, in over a thousand genes, in 15,000 individuals drawn from Indian subpopulations.
Journal ArticleDOI
Association of genetic polymorphisms in glutathione S-transferases and susceptibility to head and neck cancer.
Madhu Singh,Parag P. Shah,Arvind P. Singh,Munindra Ruwali,Neeraj Mathur,Mohan C. Pant,Devendra Parmar +6 more
TL;DR: Evidence that GST polymorphism modifies the susceptibility to head and neck squamous cell carcinoma is provided and importance of gene-environment interaction in modulating the risk is demonstrated in modifying the risk to HNSCC is demonstrated.
Journal ArticleDOI
Polymorphism in environment responsive genes and association with Parkinson disease.
Madhu Singh,Anwar Jamal Khan,Parag P. Shah,Rakesh Shukla,Rakesh Shukla,Vinay K. Khanna,Devendra Parmar +6 more
TL;DR: The data suggest that polymorphism in the genes involved in detoxification and dopamine regulation may modulate the susceptibility to PD and could be important risk factors in the pathogenesis of PD.
Journal ArticleDOI
Interaction of cytochrome P4501A1 genotypes with other risk factors and susceptibility to lung cancer.
Parag P. Shah,Arvind P. Singh,Madhu Singh,Neeraj Mathur,Mohan C. Pant,Bhartendu Nath Mishra,Devendra Parmar +6 more
TL;DR: The lung cancer risk was increased several two-to fourfold in the patients carrying the genotype combinations of CYP1A1*2A and GSTM1 suggesting the role of gene-gene interaction in lung cancer.