Tatsuki Koyama

TL;DR: Men treated for localized prostate cancer commonly had declines in all functional domains during 15 years of follow-up, and no significant relative differences in disease-specific functional outcomes were observed among men undergoing prostatectomy or radiotherapy.

TL;DR: Clinical predictors predicted mortality with an area under the ROC curve of 0.82 and the best performing biomarkers were the neutrophil chemotactic factor, IL-8, and SP-D, supporting the concept that acute inflammation and alveolar epithelial injury are important pathogenetic pathways in human ALI/ARDS.

TL;DR: Radical prostatectomy was associated with a greater decrease in sexual function and urinary incontinence after 3 years and was related with fewer urinary irritative symptoms than active surveillance; however, no meaningful differences existed in either bowel or hormonal function beyond 12 months or in in other domains of health-related quality-of-life measures.

TL;DR: The RALE score can be used to assess both the extent of pulmonary oedema and the severity of ARDS, by utilising information that is already obtained routinely, safely and inexpensively in every patient with ARDS.

TL;DR: Altered levels of plasma biomarkers may be useful biologic confirmation of the diagnosis of ARDS in patients with sepsis, and also potentially for selecting patients for clinical trials that are designed to reduce lung epithelial injury.