T
Tetsuhiko Yoshimura
Researcher at Oklahoma Medical Research Foundation
Publications - 96
Citations - 2857
Tetsuhiko Yoshimura is an academic researcher from Oklahoma Medical Research Foundation. The author has contributed to research in topics: Electron paramagnetic resonance & Nitric oxide. The author has an hindex of 30, co-authored 96 publications receiving 2755 citations.
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Journal ArticleDOI
Comparative genome analysis of Lactobacillus reuteri and Lactobacillus fermentum reveal a genomic island for reuterin and cobalamin production
Hidetoshi Morita,Hidehiro Toh,Shinji Fukuda,Hiroshi Horikawa,Kenshiro Oshima,Takehito Suzuki,Masaru Murakami,Shin Hisamatsu,Yukio Kato,Tatsuya Takizawa,Hideo Fukuoka,Tetsuhiko Yoshimura,Kikuji Itoh,Daniel J. O'Sullivan,Larry L. McKay,Hiroshi Ohno,Jun Kikuchi,Jun Kikuchi,Toshio Masaoka,Masahira Hattori +19 more
TL;DR: Two-dimensional nuclear magnetic resonance (2D-NMR) with 13C3-glycerol demonstrated that L. reuteri JCM 1112T could convert glycerol to reuterin in vivo, substantiating the potential of L.ReuteriJCM 11 12T to produce reuterIn in the intestine.
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In vivo EPR detection and imaging of endogenous nitric oxide in lipopolysaccharide-treated mice
Tetsuhiko Yoshimura,Hidekatsu Yokoyama,Satoshi Fujii,Fusako Takayama,Kazuo Oikawa,Hitoshi Kamada +5 more
TL;DR: In vivo EPR imaging of endogenous NO, trapped by an Fe-DTCS complex, in the abdomen of a live mouse is reported, the first report on EPR Imaging of endogenous free radicals produced in vivo.
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Nitrosothiol formation catalyzed by ceruloplasmin. Implication for cytoprotective mechanism in vivo.
Katsuhisa Inoue,Takaaki Akaike,Yoichi Miyamoto,Tatsuya Okamoto,Tomohiro Sawa,Masaki Otagiri,Shinnichiro Suzuki,Tetsuhiko Yoshimura,Hiroshi Maeda +8 more
TL;DR: It is suggested that CP plays an important catalytic role in RS-NO formation, which may contribute to its potent antioxidant and cytoprotective activities in vivo in mammalian biological systems.
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Oxygen and One Reducing Equivalent Are Both Required for the Conversion of α-Hydroxyhemin to Verdoheme in Heme Oxygenase
Kathryn Mansfield Matera,Satoshi Takahashi,Hiroshi Fujii,Hong Zhou,Kazunobu Ishikawa,Tetsuhiko Yoshimura,Denis L. Rousseau,Denis L. Rousseau,Tadashi Yoshida,Masao Ikeda-Saito +9 more
TL;DR: It is concluded that the catalytic conversion of ferric α-hydroxyheme to verdoheme by heme oxygenase requires molecular oxygen and one reducing equivalent.
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Toll-like receptor (TLR) 2 induced through TLR4 signaling initiated by Helicobacter pylori cooperatively amplifies iNOS induction in gastric epithelial cells
Kaname Uno,Katsuaki Kato,Tomoaki Atsumi,Takehito Suzuki,Jun Yoshitake,Hidetoshi Morita,Shuichi Ohara,Yashige Kotake,Tooru Shimosegawa,Tetsuhiko Yoshimura +9 more
TL;DR: A positive correlation between TLR2 and TLR4 expression and iNOS induction may constitute a mechanism for stimulating the innate immune response against various bacterial pathogens, including H. pylori-LPS and interferon-gamma.