T
Thomas P. Shanley
Researcher at Northwestern University
Publications - 59
Citations - 2814
Thomas P. Shanley is an academic researcher from Northwestern University. The author has contributed to research in topics: Extracorporeal membrane oxygenation & Intensive care. The author has an hindex of 24, co-authored 59 publications receiving 2062 citations. Previous affiliations of Thomas P. Shanley include University of Arizona & Boston Children's Hospital.
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Journal ArticleDOI
Multiplex serum cytokine immunoassay using nanoplasmonic biosensor microarrays.
Pengyu Chen,Meng Ting Chung,Walker M. McHugh,Robert Nidetz,Yuwei Li,Jianping Fu,Timothy T. Cornell,Thomas P. Shanley,Katsuo Kurabayashi +8 more
TL;DR: A high-throughput, label-free, multiarrayed LSPR optical biosensor device with 480 nanoplasmonic sensing spots in microfluidic channel arrays is developed and the ability to monitor the inflammatory responses of infants following cardiopulmonary bypass (CPB) surgery through tracking the time-course variations of their serum cytokines is demonstrated.
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Developing a clinically feasible personalized medicine approach to pediatric septic shock.
Hector R. Wong,Natalie Z. Cvijanovich,Nick Anas,Geoffrey L. Allen,Neal J. Thomas,Michael T. Bigham,Scott L. Weiss,Julie C. Fitzgerald,Paul A. Checchia,Keith Meyer,Thomas P. Shanley,Michael W. Quasney,Mark W. Hall,Rainer Gedeit,Robert J. Freishtat,Jeffrey Nowak,Raj S. Shekhar,Shira J. Gertz,Emily Dawson,Kelli Howard,Kelli Harmon,Eileen Beckman,Erin Frank,Christopher J. Lindsell +23 more
TL;DR: A gene expression-based classification method for pediatric septic shock that meets the time constraints of the critical care environment, and can potentially inform therapeutic decisions is developed and tested.
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Factors Associated with Bleeding and Thrombosis in Children Receiving Extracorporeal Membrane Oxygenation.
Heidi J. Dalton,Ron W Reeder,Pamela Garcia-Filion,Richard Holubkov,Robert A. Berg,Athena F. Zuppa,Frank W. Moler,Thomas P. Shanley,Murray M. Pollack,Christopher J. L. Newth,John T. Berger,David L. Wessel,Joseph A. Carcillo,Michael J. Bell,Sabrina M. Heidemann,Kathleen L. Meert,Rick Harrison,Allan Doctor,Robert F. Tamburro,J. Michael Dean,Tammara L. Jenkins,Carol Nicholson +21 more
TL;DR: In this article, a prospective, observational cohort study in pediatric, cardiac, and neonatal intensive care units in eight hospitals, carried out from December 2012 to September 2014, was carried out to measure the incidence of bleeding (blood loss requiring transfusion or intracranial hemorrhage) and thrombosis during ECMO support.
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The Pediatric Risk of Mortality Score: Update 2015*
Murray M. Pollack,Richard Holubkov,Tomohiko Funai,J. Michael Dean,John T. Berger,David L. Wessel,Kathleen L. Meert,Robert A. Berg,Christopher J. L. Newth,Rick Harrison,Joseph A. Carcillo,Heidi J. Dalton,Thomas P. Shanley,Tammara L. Jenkins,Robert F. Tamburro,Carol Nicholson +15 more
TL;DR: The new Pediatric Risk of Mortality data collection methods include significant improvements that minimize the potential for bias and errors, and the newPediatric risk-based prediction algorithm for survival and death has excellent prediction performance.
Journal ArticleDOI
Association of bleeding and thrombosis with outcome in extracorporeal life support.
Heidi J. Dalton,Pamela Garcia-Filion,Richard Holubkov,Frank W. Moler,Thomas P. Shanley,Sabrina M. Heidemann,Kathleen L. Meert,Robert A. Berg,John T. Berger,Joseph A. Carcillo,Christopher J. L. Newth,Rick Harrison,Allan Doctor,Peter Rycus,J. Michael Dean,Tammara L. Jenkins,Carol Nicholson +16 more
TL;DR: Retrospective analysis of patients reported to the Extracorporeal Life Support Organization registry from eight Collaborative Pediatric Critical Care Research Network centers between 2005 and 2011 found bleeding and thrombosis remain common complications in patients undergoing extracorpiological life support.