J
Julie C. Fitzgerald
Researcher at Children's Hospital of Philadelphia
Publications - 180
Citations - 11211
Julie C. Fitzgerald is an academic researcher from Children's Hospital of Philadelphia. The author has contributed to research in topics: Medicine & Sepsis. The author has an hindex of 38, co-authored 136 publications receiving 7241 citations. Previous affiliations of Julie C. Fitzgerald include University of Pennsylvania & Wistar Institute.
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Journal ArticleDOI
Multisystem Inflammatory Syndrome in U.S. Children and Adolescents.
Leora R. Feldstein,Leora R. Feldstein,Erica B. Rose,Erica B. Rose,Steven M. Horwitz,Jennifer P. Collins,Margaret M Newhams,Mary Beth F. Son,Jane W. Newburger,Lawrence C. Kleinman,Sabrina M. Heidemann,Amarilis A. Martin,Aalok R. Singh,Simon Li,Keiko M. Tarquinio,Preeti Jaggi,Matthew E. Oster,Sheemon P. Zackai,Jennifer K. Gillen,Adam J. Ratner,Rowan Walsh,Julie C. Fitzgerald,Michael A. Keenaghan,Hussam Alharash,Sule Doymaz,Katharine N. Clouser,John S. Giuliano,Anjali Gupta,Robert M. Parker,Aline B Maddux,Vinod Havalad,Stacy Ramsingh,Hulya Bukulmez,Tamara T. Bradford,Lincoln S. Smith,Mark W Tenforde,Christopher L. Carroll,Becky J. Riggs,Shira J. Gertz,Ariel Daube,Amanda N Lansell,Alvaro Coronado Munoz,Charlotte V. Hobbs,Kimberly Marohn,Natasha B. Halasa,Manish M. Patel,Manish M. Patel,Adrienne G. Randolph +47 more
TL;DR: Multisystem inflammatory syndrome in children associated with SARS-CoV-2 led to serious and life-threatening illness in previously healthy children and adolescents.
Journal ArticleDOI
Identification of Predictive Biomarkers for Cytokine Release Syndrome after Chimeric Antigen Receptor T cell Therapy for Acute Lymphoblastic Leukemia
David T. Teachey,David T. Teachey,Simon F. Lacey,Pamela A. Shaw,J. Joseph Melenhorst,Shannon L. Maude,Noelle V. Frey,Edward Pequignot,Vanessa E. Gonzalez,Fang Chen,Jeffrey Finklestein,David M. Barrett,Scott L. Weiss,Julie C. Fitzgerald,Robert A. Berg,Richard Aplenc,Colleen Callahan,Susan R. Rheingold,Zhaohui Zheng,Stefan Rose-John,Jason C. White,Farzana Nazimuddin,Gerald Wertheim,Bruce L. Levine,Carl H. June,David L. Porter,Stephan A. Grupp +26 more
TL;DR: The first models that can accurately predict which patients are likely to develop severe CRS before they become critically ill are developed, which improves understanding of CRS biology and may guide future cytokine-directed therapy.
Journal ArticleDOI
Global Epidemiology of Pediatric Severe Sepsis: The Sepsis Prevalence, Outcomes, and Therapies Study
Scott L. Weiss,Julie C. Fitzgerald,John Pappachan,Derek S. Wheeler,Juan C. Jaramillo-Bustamante,Asma Salloo,Sunit C. Singhi,Simon Erickson,Jason Roy,Jenny Bush,Vinay M. Nadkarni,Neal J. Thomas +11 more
TL;DR: Pediatric severe sepsis remains a burdensome public health problem, with prevalence, morbidity, and mortality rates similar to those reported in critically ill adult populations.
Journal ArticleDOI
American College of Critical Care Medicine Clinical Practice Parameters for Hemodynamic Support of Pediatric and Neonatal Septic Shock.
Alan L. Davis,Joseph A. Carcillo,Rajesh K. Aneja,Andreas J. Deymann,John C. Lin,Trung C. Nguyen,Regina Okhuysen-Cawley,Monica S. Relvas,Ranna A. Rozenfeld,Peter Skippen,Bonnie J. Stojadinovic,Eric A. Williams,Tim S. Yeh,Fran Balamuth,Joe Brierley,Allan R. de Caen,Ira M. Cheifetz,Karen Choong,Edward E. Conway,Timothy T. Cornell,Allan Doctor,Marc Andre Dugas,Jonathan D. Feldman,Julie C. Fitzgerald,Heidi R. Flori,James D. Fortenberry,Ana Lia Graciano,Bruce M. Greenwald,Mark W. Hall,Yong Yun Han,Lynn J. Hernan,Jose Irazuzta,Elizabeth Iselin,Elise W. van der Jagt,Howard E. Jeffries,Saraswati Kache,Chhavi Katyal,Niranjan Kissoon,Alexander A. Kon,Martha C. Kutko,Graeme MacLaren,Graeme MacLaren,Timothy M. Maul,Renuka Mehta,Fola Odetola,Kristine A Parbuoni,Raina Paul,Mark J. Peters,Suchitra Ranjit,Karin Reuter-Rice,Eduardo Schnitzler,Halden F. Scott,Adalberto Torres,Jacki Weingarten-Abrams,Scott L. Weiss,Jerry J. Zimmerman,Aaron L. Zuckerberg +56 more
TL;DR: A major new recommendation in the 2014 update of the 2007 American College of Critical Care Medicine “Clinical Guidelines for Hemodynamic Support of Neonates and Children with Septic Shock” is consideration of institution—specific use of a recognition bundle containing a trigger tool for rapid identification of patients with septic shock.
Journal ArticleDOI
Cytokine release syndrome after blinatumomab treatment related to abnormal macrophage activation and ameliorated with cytokine-directed therapy.
David T. Teachey,David T. Teachey,Susan R. Rheingold,Susan R. Rheingold,Shannon L. Maude,Shannon L. Maude,Gerhard Zugmaier,David M. Barrett,David M. Barrett,Alix E. Seif,Alix E. Seif,Kim E. Nichols,Kim E. Nichols,Erica Suppa,Michael Kalos,Robert A. Berg,Robert A. Berg,Julie C. Fitzgerald,Julie C. Fitzgerald,Richard Aplenc,Richard Aplenc,Lia Gore,Stephan A. Grupp,Stephan A. Grupp +23 more
TL;DR: Patients treated with T cell-activating therapies, including blinatumomab, should be monitored for HLH, and cytokine-directed therapy may be considered in cases of life-threatening CRS.