T
Thomas Ruzicka
Researcher at University of Düsseldorf
Publications - 308
Citations - 17039
Thomas Ruzicka is an academic researcher from University of Düsseldorf. The author has contributed to research in topics: Receptor & Lupus erythematosus. The author has an hindex of 68, co-authored 308 publications receiving 16302 citations.
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Journal ArticleDOI
Adverse Effects of Topical Glucocorticosteroids
TL;DR: An updated review of local and systemic adverse effects upon administration of topical corticosteroids, including the latest FDA report on the safety of such steroids in children, is provided.
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CCL27-CCR10 interactions regulate T cell-mediated skin inflammation.
Bernhard Homey,Harri Alenius,Anja Müller,Hortensia Soto,Edward P. Bowman,Wei Yuan,Leslie McEvoy,Antti Lauerma,Till Assmann,Erich Bünemann,Maili Lehto,Henrik Wolff,David C. Yen,Heather Marxhausen,Wayne To,Jonathon D. Sedgwick,Thomas Ruzicka,Percy Lehmann,Albert Zlotnik +18 more
TL;DR: It is reported that most skin-infiltrating lymphocytes in patients suffering from psoriasis, atopic or allergic-contact dermatitis express CCR10, indicating that CCL27–CCR10 interactions have a pivotal role in T cell–mediated skin inflammation.
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A Role for Th1 and Th2 Cells in the Immunopathogenesis of Atopic Dermatitis
Markus Grewe,Carla A.F.M. Bruijnzeel-Koomen,Erwin Schöpf,T. Thepen,Alice G Langeveld-Wildschut,Thomas Ruzicka,Jean Krutmann +6 more
TL;DR: It is proposed that the development of skin lesions in AD patients results from sequential activation of T helper 2 (Th2)- and Th1-type cells.
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Up-Regulation of Macrophage Inflammatory Protein-3α/CCL20 and CC Chemokine Receptor 6 in Psoriasis
Bernhard Homey,Marie-Caroline Dieu-Nosjean,Andrea Wiesenborn,Catherine Massacrier,Jean-Jacques Pin,Elizabeth Oldham,Daniel Catron,Matthew E. Buchanan,Anja Müller,Rene de Waal Malefyt,Glenn Deng,Rocio Orozco,Thomas Ruzicka,Percy Lehmann,Serge Lebecque,Christophe Caux,Albert Zlotnik +16 more
TL;DR: C cultured primary keratinocytes, dermal fibroblasts, and dermal microvascular endothelial and dendritic cells are major sources of CCL20, and that the expression of this chemokine can be induced by proinflammatory mediators such as TNF-α/IL-1β, CD40 ligand, IFN-γ, or IL-17 are shown.
Journal ArticleDOI
A short-term trial of tacrolimus ointment for atopic dermatitis. European Tacrolimus Multicenter Atopic Dermatitis Study Group
Thomas Ruzicka,Thomas Bieber,Erwin Schöpf,Andris Rubins,Attila Dobozy,Jan D. Bos,Stefania Jabłońska,Imitiaz Ahmed,Kristian Thestrup-Pedersen,Francois Daniel,Aldo Finzi,Sakari Reitamo +11 more
TL;DR: The short-term application of tacrolimus ointment is effective in the treatment of atopic dermatitis, with the sensation of burning being the main side effect.