M
Marie-Caroline Dieu-Nosjean
Researcher at University of Paris
Publications - 82
Citations - 12410
Marie-Caroline Dieu-Nosjean is an academic researcher from University of Paris. The author has contributed to research in topics: Immune system & Tumor microenvironment. The author has an hindex of 46, co-authored 75 publications receiving 10320 citations. Previous affiliations of Marie-Caroline Dieu-Nosjean include Schering-Plough & French Institute of Health and Medical Research.
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Journal ArticleDOI
Immune infiltration in human tumors: a prognostic factor that should not be ignored.
Franck Pagès,Jérôme Galon,Jérôme Galon,Jérôme Galon,Marie-Caroline Dieu-Nosjean,Marie-Caroline Dieu-Nosjean,Marie-Caroline Dieu-Nosjean,Eric Tartour,Catherine Sautès-Fridman,Catherine Sautès-Fridman,Catherine Sautès-Fridman,Wolf H. Fridman +11 more
TL;DR: An immune scoring based on the type, density and location of lymphocyte infiltrates as a novel prognostic factor for use in addition to tumor node metastasis staging to predict disease-free survival and to aid in decisions regarding adjuvant therapies in early stage human cancers.
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IL-31: A new link between T cells and pruritus in atopic skin inflammation
Enikö Sonkoly,Anja Müller,Antti Lauerma,Andor Pivarcsi,Hortensia Soto,Lajos Kemény,Harri Alenius,Marie-Caroline Dieu-Nosjean,Stephan Meller,Juliane Rieker,Martin Steinhoff,Thomas K. Hoffmann,Thomas Ruzicka,Albert Zlotnik,Bernhard Homey +14 more
TL;DR: The findings provide a new link among staphylococcal colonization, subsequent T-cell recruitment/activation, and pruritus induction in patients with atopic dermatitis, and show that IL-31 may represent a novel target for antipruritic drug development.
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Long-Term Survival for Patients With Non–Small-Cell Lung Cancer With Intratumoral Lymphoid Structures
Marie-Caroline Dieu-Nosjean,Martine Antoine,Claire Danel,Didier Heudes,Marie Wislez,Virginie Poulot,Nathalie Rabbe,Ludivine Laurans,Eric Tartour,Luc de Chaisemartin,Serge Lebecque,Wolf H. Fridman,Jacques Cadranel +12 more
TL;DR: Univariate analysis showed that the density of mature DCs was highly associated with a favorable clinical outcome (overall, disease-specific, and disease-free survival), suggesting that Ti-BALT may participate in antitumoral immunity.
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Matrix architecture defines the preferential localization and migration of T cells into the stroma of human lung tumors
Hélène Salmon,Katarzyna Franciszkiewicz,Diane Damotte,Marie-Caroline Dieu-Nosjean,Pierre Validire,Alain Trautmann,Fathia Mami-Chouaib,Emmanuel Donnadieu +7 more
TL;DR: By combining immunostaining and real-time imaging in viable slices of human lung tumors, it is revealed that the density and the orientation of the stromal extracellular matrix likely play key roles in controlling the migration of T cells.
Journal ArticleDOI
Up-Regulation of Macrophage Inflammatory Protein-3α/CCL20 and CC Chemokine Receptor 6 in Psoriasis
Bernhard Homey,Marie-Caroline Dieu-Nosjean,Andrea Wiesenborn,Catherine Massacrier,Jean-Jacques Pin,Elizabeth Oldham,Daniel Catron,Matthew E. Buchanan,Anja Müller,Rene de Waal Malefyt,Glenn Deng,Rocio Orozco,Thomas Ruzicka,Percy Lehmann,Serge Lebecque,Christophe Caux,Albert Zlotnik +16 more
TL;DR: C cultured primary keratinocytes, dermal fibroblasts, and dermal microvascular endothelial and dendritic cells are major sources of CCL20, and that the expression of this chemokine can be induced by proinflammatory mediators such as TNF-α/IL-1β, CD40 ligand, IFN-γ, or IL-17 are shown.