T
Thomas Wagner
Researcher at Heriot-Watt University
Publications - 227
Citations - 9531
Thomas Wagner is an academic researcher from Heriot-Watt University. The author has contributed to research in topics: Total organic carbon & Cretaceous. The author has an hindex of 46, co-authored 213 publications receiving 8530 citations. Previous affiliations of Thomas Wagner include Newcastle University & Dresden University of Technology.
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Journal ArticleDOI
A mammalian model for Laron syndrome produced by targeted disruption of the mouse growth hormone receptor/binding protein gene (the Laron mouse)
Yihua Zhou,Bixiong C. Xu,Hiralal G. Maheshwari,Li He,Michael Reed,Maria Lozykowski,Shigeru Okada,Lori Cataldo,Karen Coschigamo,Thomas Wagner,Gerhard Baumann,John J. Kopchick +11 more
TL;DR: The findings indicate that the G HR/BP-deficient mouse (Laron mouse) is a suitable model for human Laron syndrome that will prove useful for the elucidation of many aspects of GHR/BP function that cannot be obtained in humans.
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Early diagenesis of organic matter from sediments of the eastern subtropical Atlantic: evidence from stable nitrogen and carbon isotopes
TL;DR: In this article, the authors determined concentrations and isotopic compositions of inorganic nitrogen (IN), organic nitrogen (ON), total nitrogen (TN), and total organic carbon (TOC) on one short core recovered from sediments of the eastern subtropical Atlantic, between the Canary Islands and the Moroccan coast.
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Cretaceous sea-surface temperature evolution: Constraints from TEX86 and planktonic foraminiferal oxygen isotopes
Charlotte L O'Brien,Stuart A. Robinson,Richard D. Pancost,Jaap S. Sinninghe Damsté,Stefan Schouten,Daniel J. Lunt,Heiko Alsenz,André Bornemann,André Bornemann,Cinzia Bottini,Simon C. Brassell,Alexander Farnsworth,Astrid Forster,Brian T. Huber,Gordon N. Inglis,Hugh C. Jenkyns,Christian Linnert,Kate Littler,Paul J. Markwick,Alison McAnena,Jörg Mutterlose,B. David A. Naafs,Wilhelm Püttmann,Appy Sluijs,Niels A. G. M. van Helmond,Johan Vellekoop,Thomas Wagner,Neil Wrobel +27 more
TL;DR: In this article, a compilation and synthesis of available planktonic foraminiferal δ18O and TEX86-SST proxy data for almost the entire Cretaceous Period is presented.
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Hypoxia-inducible factor-1 (HIF-1) promotes its degradation by induction of HIF-α-prolyl-4-hydroxylases
Jan H. Marxsen,Petra Stengel,Kathrin Doege,Pekka T. Heikkinen,Terhi Jokilehto,Thomas Wagner,Wolfgang Jelkmann,Panu Jaakkola,Eric Metzen +8 more
TL;DR: A direct, negative regulatory mechanism is proposed, which limits accumulation of HIF-1alpha in Hypoxia and leads to accelerated degradation on reoxygenation after long-term hypoxia, which demonstrates functional relevance of the present results.
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Microinjection of a rabbit beta-globin gene into zygotes and its subsequent expression in adult mice and their offspring.
Thomas Wagner,Peter Hoppe,Joseph D. Jollick,David R. Scholl,Richard L. Hodinka,Janice B. Gault +5 more
TL;DR: A gene coding for rabbit beta-globin is transferred into the male pronucleus of mouse zygotes by direct microinjection to allow the introduction and expression of a broad range of genetic elements in mammals.