T
Tien Peng
Researcher at University of California, San Francisco
Publications - 28
Citations - 1728
Tien Peng is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Stem cell & Biology. The author has an hindex of 11, co-authored 22 publications receiving 1227 citations. Previous affiliations of Tien Peng include Peking Union Medical College & Cardiovascular Institute of the South.
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Journal ArticleDOI
Distinct functions for Wnt/β-catenin in hair follicle stem cell proliferation and survival and interfollicular epidermal homeostasis
Yeon Sook Choi,Yuhang Zhang,Yuhang Zhang,Mingang Xu,Yongguang Yang,Mayumi Ito,Tien Peng,Zheng Cui,Andras Nagy,Anna-Katerina Hadjantonakis,Richard A. Lang,George Cotsarelis,Thomas Andl,Edward E. Morrisey,Sarah E. Millar +14 more
TL;DR: A broader role is unexpectedly discovered for Wnt/β-catenin signaling in contributing to progenitor cell proliferation in nonhairy epithelia and interfollicular epidermis under homeostatic, but not inflammatory, conditions.
Journal ArticleDOI
Emergence of a Wave of Wnt Signaling that Regulates Lung Alveologenesis by Controlling Epithelial Self-Renewal and Differentiation
David B. Frank,Tien Peng,Jarod A. Zepp,Melinda Snitow,Tiffaney Vincent,Ian J. Penkala,Zheng Cui,Michael J. Herriges,Michael Morley,Su Zhou,Min Min Lu,Edward E. Morrisey +11 more
TL;DR: In this article, a Wnt-responsive alveolar epithelial cell sublineage, called the axin2+alveolar type 2 cell, or AT2Axin2, was demonstrated during alveologenesis.
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Adventitial Stromal Cells Define Group 2 Innate Lymphoid Cell Tissue Niches
Madelene W. Dahlgren,Stephen M. Jones,Kelly M. Cautivo,Alexandra Dubinin,Jorge F. Ortiz-Carpena,Sepideh Farhat,Kevin Shengyang Yu,Katharine Lee,Chaoqun Wang,Anna V. Molofsky,Aaron D. Tward,Matthew F. Krummel,Tien Peng,Ari B. Molofsky +13 more
TL;DR: 3D imaging data indicate that adventitial niches are conserved sites where ASCs regulate type 2 lymphocyte expansion and function, which are in part dependent on ASC‐derived IL‐33.
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Coordination of heart and lung co-development by a multipotent cardiopulmonary progenitor
Tien Peng,Ying Tian,Cornelis J. Boogerd,Min Min Lu,Rachel S. Kadzik,Kathleen M. Stewart,Sylvia M. Evans,Edward E. Morrisey +7 more
TL;DR: This work shows that the murine pulmonary vasculature develops even in the absence of lung development, and identifies a novel population of multipotent cardiopulmonary progenitors that coordinates heart and lung co-development that is required for adaptation to terrestrial existence.
Journal ArticleDOI
Hedgehog actively maintains adult lung quiescence and regulates repair and regeneration
Tien Peng,David B. Frank,Rachel S. Kadzik,Michael Morley,Komal S. Rathi,Tao Wang,Su Zhou,Lan Cheng,Min Min Lu,Edward E. Morrisey +9 more
TL;DR: It is demonstrated that quiescence in the adult lung is an actively maintained state and is regulated by hedgehog signalling, and deregulation of hedgehog during injury leads to aberrant repair and regeneration in the lung.