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Anna-Katerina Hadjantonakis

Researcher at Memorial Sloan Kettering Cancer Center

Publications -  209
Citations -  17693

Anna-Katerina Hadjantonakis is an academic researcher from Memorial Sloan Kettering Cancer Center. The author has contributed to research in topics: Embryonic stem cell & Epiblast. The author has an hindex of 71, co-authored 195 publications receiving 14616 citations. Previous affiliations of Anna-Katerina Hadjantonakis include Kettering University & Children's Medical Research Institute.

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Promotion of Trophoblast Stem Cell Proliferation by FGF4

TL;DR: A culture of mouse blastocysts or early postimplantation trophoblasts in the presence of fibroblast growth factor 4 (FGF4) permitted the isolation of permanent trophoblast stem cell lines that exclusively contributed to the trophoplast lineage in vivo in chimeras.
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Guidelines and definitions for research on epithelial–mesenchymal transition

Jing Yang, +47 more
TL;DR: This Consensus Statement is the outcome of a 2-year-long discussion among EMT researchers and aims to both clarify the nomenclature and provide definitions and guidelines for EMT research in future publications to reduce misunderstanding and misinterpretation of research data generated in various experimental models.
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Generating green fluorescent mice by germline transmission of green fluorescent ES cells

TL;DR: A mouse embryonic stem (ES) cell lines expressing EGFP is established, which can be propagated in culture, reintroduced into mice, or induced to differentiate in vitro, while still maintaining ubiquitous EGFP expression.
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Distinct sequential cell behaviours direct primitive endoderm formation in the mouse blastocyst.

TL;DR: The events leading to PrE and EPI lineage segregation in the mouse are investigated by combining live imaging of embryos expressing a histone H2B-GFP fusion protein reporter under the control of Pdgfra regulatory elements with the analysis of lineage-specific markers.
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Mice lacking both presenilin genes exhibit early embryonic patterning defects.

TL;DR: It is concluded that the presenilins play a widespread role in embryogenesis, that there is a functional redundancy between PS1 and PS2, and that both vertebrate presenILins, like their invertebrate homologs, are essential for Notch signaling.