Mayumi Ito

TL;DR: It is shown that ablation of bulge cells by targeting them with a suicide gene encoding herpes simplex virus thymidine kinase leads to complete loss of hair follicles but survival of the epidermis, indicating that bulge stem cells respond rapidly to epidermal wounding by generating short-lived 'transient amplifying' cells responsible for acute wound repair.

TL;DR: It is shown that, after wounding, hair follicles form de novo in genetically normal adult mice, and these remarkable regenerative capabilities of the adult support the notion that wounding induces an embryonic phenotype in skin, and that this provides a window for manipulation of hair follicle neogenesis by Wnt proteins.

TL;DR: This article will focus on the contribution of skin appendages to wound healing and, conversely, skin appendage regeneration following injuries.

TL;DR: The myofibroblast is identified as a plastic cell type that may be manipulated to treat scars in humans through the bone morphogenetic protein signaling pathway and adipocyte transcription factors expressed during development.

TL;DR: A role for Wnt signaling in the regulation of McSCs is defined and a mechanism for regeneration of complex organs through collaboration between heterotypic stem cell populations is illustrated.