T
Tiffany Bouchery
Researcher at École Polytechnique Fédérale de Lausanne
Publications - 34
Citations - 1047
Tiffany Bouchery is an academic researcher from École Polytechnique Fédérale de Lausanne. The author has contributed to research in topics: Nippostrongylus brasiliensis & Immune system. The author has an hindex of 13, co-authored 28 publications receiving 747 citations. Previous affiliations of Tiffany Bouchery include Malaghan Institute of Medical Research & Monash University.
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Journal ArticleDOI
Neuronal regulation of type 2 innate lymphoid cells via neuromedin U
Vânia Cardoso,Julie Chesné,Hélder Ribeiro,Bethania García-Cassani,Tânia Carvalho,Tiffany Bouchery,Kathleen Shah,Nuno L. Barbosa-Morais,Nicola L. Harris,Henrique Veiga-Fernandes +9 more
TL;DR: It is shown that neuromedin U (NMU) in mice is a fast and potent regulator of type 2 innate immunity in the context of a functional neuron–ILC2 unit, and this work reveals that neuron–ilC2 cell units confer immediate tissue protection through coordinated neuroimmune sensory responses.
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ILC2s and T cells cooperate to ensure maintenance of M2 macrophages for lung immunity against hookworms
Tiffany Bouchery,Ryan Kyle,Mali Camberis,Amy L. Shepherd,Kara J. Filbey,Adam Alexander T. Smith,Marina Harvie,Gavin F. Painter,Karen A. Johnston,Peter M. Ferguson,Rohit Jain,Ben Roediger,Brett Delahunt,Wolfgang Weninger,Elizabeth Forbes-Blom,Graham Le Gros +15 more
TL;DR: These results broaden understanding of ILC2's role in immunity to helminths by demonstrating that they not only act as alarmin sensors, but can also be sustained by CD4(+) T cells, ensuring both the prompt activation and the maintenance of IL-13-dependent M2 macrophage immunity in the lung.
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Secreted Proteomes of Different Developmental Stages of the Gastrointestinal Nematode Nippostrongylus brasiliensis
Javier Sotillo,Alejandro Sanchez-Flores,Cinzia Cantacessi,Yvonne Harcus,Darren Pickering,Tiffany Bouchery,Mali Camberis,Shiau Choot Tang,Paul R. Giacomin,Jason Mulvenna,Makedonka Mitreva,Matthew Berriman,Graham Legros Legros,Rick M. Maizels,Alex Loukas +14 more
TL;DR: Phylogenetic analyses of defined protein families and global gene similarity analyses showed that N. brasiliensis has a greater degree of conservation with human hookworm than other model nematodes examined.
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The symbiotic role of Wolbachia in Onchocercidae and its impact on filariasis
TL;DR: The contribution of Wolbachia to the survival of the filariae and to the development of pathology is highlighted and the infection control implications for filariases are debated.
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The Differentiation of CD4(+) T-Helper Cell Subsets in the Context of Helminth Parasite Infection.
TL;DR: It is argued for a re-evaluation of the original Th2 paradigm and how the observed plasticity of the T-helper subsets may enable the parasitized host to achieve an appropriate compromise between elimination, tissue repair, containment, and pathology.