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Tim Wharton

Researcher at Massachusetts Institute of Technology

Publications -  12
Citations -  1187

Tim Wharton is an academic researcher from Massachusetts Institute of Technology. The author has contributed to research in topics: Photodynamic therapy & Photosensitizer. The author has an hindex of 9, co-authored 12 publications receiving 1070 citations.

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Photodynamic therapy with fullerenes

TL;DR: Fullerenes are a class of closed-cage nanomaterials made exclusively from carbon atoms that absorb visible light, have a high triplet yield and can generate reactive oxygen species upon illumination, suggesting a possible role of fullerene in photodynamic therapy.
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Cationic Fullerenes Are Effective and Selective Antimicrobial Photosensitizers

TL;DR: Six functionalized C(60) compounds with one, two, or three hydrophilic or cationic groups in combination with white light against gram-positive bacteria, gram-negative bacteria, and fungi are compared.
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Functionalized fullerenes mediate photodynamic killing of cancer cells: Type I versus Type II photochemical mechanism.

TL;DR: It is concluded that certain functionalized fullerenes have potential as novel PDT agents and phototoxicity may be mediated both by superoxide and by singlet oxygen.