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Ulf Müller-Ladner

Researcher at University of Giessen

Publications -  644
Citations -  32784

Ulf Müller-Ladner is an academic researcher from University of Giessen. The author has contributed to research in topics: Medicine & Arthritis. The author has an hindex of 77, co-authored 590 publications receiving 27658 citations. Previous affiliations of Ulf Müller-Ladner include University of Regensburg & University of Genoa.

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Langfassung zur S2e-Leitlinie Gichtarthritis (fachärztlich)

TL;DR: The present work presents a meta-analyses of the prophylactic and motivational properties of canine coronavirus, which attacks the immune system through a number of mechanisms, including “cell reprograming” and “self-consistency”.
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Reduction of in vitro invasion and in vivo cartilage degradation in a SCID mouse model by loss of function of the fibrinolytic system of rheumatoid arthritis synovial fibroblasts.

TL;DR: The decrease in uPAR expression in RA SFs reduced invasion of human cartilage in vitro and in the SCID mouse model, and significant inhibition of cartilage invasion was obtained in vivo with uPAR antisense treatment, while uPA inhibition was inefficient.
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The SCID mouse model: novel therapeutic targets – lessons from gene transfer

TL;DR: Modulation of both pathways by gene transfer approaches in the SCID mouse model is a feasible method aimed at identifying novel targets for the prevention of cartilage destruction in RA.