V
Vanessa Deveaux
Researcher at French Institute of Health and Medical Research
Publications - 24
Citations - 2141
Vanessa Deveaux is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Cannabinoid receptor type 2 & Cannabinoid receptor. The author has an hindex of 15, co-authored 24 publications receiving 1945 citations. Previous affiliations of Vanessa Deveaux include University of Paris.
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Journal ArticleDOI
CB1 cannabinoid receptor antagonism: a new strategy for the treatment of liver fibrosis.
Fatima Teixeira-Clerc,Boris Julien,Boris Julien,Pascale Grenard,Pascale Grenard,Jeanne Tran Van Nhieu,Jeanne Tran Van Nhieu,Vanessa Deveaux,Vanessa Deveaux,Liying Li,Liying Li,Valérie Serriere-Lanneau,Valérie Serriere-Lanneau,Catherine Ledent,Ariane Mallat,Ariane Mallat,Sophie Lotersztajn,Sophie Lotersztajn +17 more
TL;DR: The study shows that CB1 receptor antagonists hold promise for the treatment of liver fibrosis, and suggests that endocannabinoids may drive both CB2-mediated antifibrogenic effects andCB2-independent profibrogenics effects.
Journal ArticleDOI
Long term in vivo biotransformation of iron oxide nanoparticles.
Michael Levy,Nathalie Luciani,Damien Alloyeau,Dan Elgrabli,Vanessa Deveaux,Christine Péchoux,Sophie Chat,Guillaume Wang,Nidhi Vats,Francois Gendron,Cécile Factor,Sophie Lotersztajn,Alain Luciani,Claire Wilhelm,Florence Gazeau +14 more
TL;DR: A multiscale approach to study the fate of nanomagnets in the organism and evidence the biotransformation of superparamagnetic maghemite nanoparticles into poorly-magnetic iron species probably stored into ferritin proteins over a period of three months is evidence.
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Cannabinoid CB2 receptors protect against alcoholic liver disease by regulating Kupffer cell polarization in mice
Alexandre Louvet,Alexandre Louvet,Fatima Teixeira-Clerc,Fatima Teixeira-Clerc,Marie-Noële Chobert,Marie-Noële Chobert,Vanessa Deveaux,Vanessa Deveaux,Catherine Pavoine,Catherine Pavoine,Andreas Zimmer,Françoise Pecker,Françoise Pecker,Ariane Mallat,Ariane Mallat,Sophie Lotersztajn,Sophie Lotersztajn +16 more
TL;DR: It is demonstrated that CB2 receptors display beneficial effects on alcohol‐induced inflammation by regulating M1/M2 balance in Kupffer cells, thereby reducing hepatocyte steatosis via paracrine interactions between K upffer cells and hepatocytes.
Journal ArticleDOI
Cannabinoid CB2 Receptor Potentiates Obesity-Associated Inflammation, Insulin Resistance and Hepatic Steatosis
Vanessa Deveaux,Vanessa Deveaux,Thomas Cadoudal,Thomas Cadoudal,Yasukatsu Ichigotani,Yasukatsu Ichigotani,Fatima Teixeira-Clerc,Fatima Teixeira-Clerc,Alexandre Louvet,Alexandre Louvet,Sylvie Manin,Sylvie Manin,Jeanne Tran Van Nhieu,Jeanne Tran Van Nhieu,Marie Pierre Belot,Marie Pierre Belot,Andreas Zimmer,Patrick C. Even,Patrice D. Cani,Claude Knauf,Rémy Burcelin,Adeline Bertola,Adeline Bertola,Yannick Le Marchand-Brustel,Yannick Le Marchand-Brustel,Philippe Gual,Philippe Gual,Ariane Mallat,Ariane Mallat,Sophie Lotersztajn,Sophie Lotersztajn +30 more
TL;DR: These data unravel a previously unrecognized contribution of CB2 receptors to obesity-associated inflammation, insulin resistance and non-alcoholic fatty liver disease, and suggest that CB2 receptor antagonists may open a new therapeutic approach for the management of obesity- associated metabolic disorders.
Journal ArticleDOI
Elevated Expression of Osteopontin May Be Related to Adipose Tissue Macrophage Accumulation and Liver Steatosis in Morbid Obesity
Adeline Bertola,Vanessa Deveaux,Stéphanie Bonnafous,Déborah Rousseau,Rodolphe Anty,Abdelilah Wakkach,Moncef Dahman,Joan Tordjman,Karine Clément,S. McQuaid,Keith N. Frayn,Pierre-Michel Huet,Jean Gugenheim,Sophie Lotersztajn,Yannick Le Marchand-Brustel,Albert Tran,Philippe Gual +16 more
TL;DR: The modestly elevated circulating OPN levels in morbidly obese patients were not related to liver steatosis and did not appear to result from adipose tissue secretion, and in subcutaneous AT, expression of OPN was directly related to macrophage accumulation independently from liver complications.