Victor Ruotti

TL;DR: The first genome-wide, single-base-resolution maps of methylated cytosine methylation in a mammalian genome are presented, from both human embryonic stem cells and fetal fibroblasts, along with comparative analysis of messenger RNA and small RNA components of the transcriptome, several histone modifications, and sites of DNA–protein interaction for several key regulatory factors.

TL;DR: Somatic cell nuclear transfer as discussed by the authors permits transacting factors resident in the mammalian oocyte to reprogram somatic cell nuclei to an undifferentiated state, which is called epigenetic activation.

TL;DR: Kendzior et al. as mentioned in this paper developed EBSeq for identifying differentially expressed (DE) genes and their corresponding isoforms on a genome-wide scale using RNA-seq experiments.

TL;DR: ProMoST is a flexible web tool that calculates the effect of single or multiple posttranslational modifications (PTMs) on protein isoelectric point (pI) and molecular weight and displays the calculated patterns as twoD gel images.

TL;DR: It is proposed that isothermal probes designed by varying the length is a viable strategy to reduce sequence bias, though imposing selection constraints on other oligonucleotide properties is also essential.