I
Igor I. Slukvin
Researcher at University of Wisconsin-Madison
Publications - 141
Citations - 22696
Igor I. Slukvin is an academic researcher from University of Wisconsin-Madison. The author has contributed to research in topics: Induced pluripotent stem cell & Stem cell. The author has an hindex of 36, co-authored 125 publications receiving 21182 citations. Previous affiliations of Igor I. Slukvin include WiCell & Wisconsin Alumni Research Foundation.
Papers
More filters
Journal ArticleDOI
Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells
Junying Yu,Maxim A. Vodyanik,Kim Smuga-Otto,Jessica Antosiewicz-Bourget,Jennifer L. Frane,Shulan Tian,Jeff Nie,Gudrun A. Jonsdottir,Victor Ruotti,Ron Stewart,Igor I. Slukvin,James A. Thomson +11 more
TL;DR: This article showed that OCT4, SOX2, NANOG, and LIN28 factors are sufficient to reprogram human somatic cells to pluripotent stem cells that exhibit the essential characteristics of embryonic stem (ES) cells.
Supporting Online Material for Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells
Junying Yu,Maxim A. Vodyanik,Kim Smuga-Otto,Jessica Antosiewicz-Bourget,Jennifer L. Frane,Shulan Tian,Jeff Nie,Gudrun A. Jonsdottir,Victor Ruotti,Ron M. Stewart,Igor I. Slukvin,James A. Thomson +11 more
TL;DR: Yu et al. as discussed by the authors proposed online material for induced pluripotent stem cell lines derived from human Somatic Cells, which can be used for transplanting human stem cells to humans.
Journal ArticleDOI
Human Induced Pluripotent Stem Cells Free of Vector and Transgene Sequences
Junying Yu,Junying Yu,Kejin Hu,Kim Smuga-Otto,Kim Smuga-Otto,Shulan Tian,Shulan Tian,Ron Stewart,Ron Stewart,Igor I. Slukvin,James A. Thomson +10 more
TL;DR: Results demonstrate that reprograming human somatic cells does not require genomic integration or the continued presence of exogenous reprogramming factors and removes one obstacle to the clinical application of human iPS cells.
Journal ArticleDOI
Epigenomic Analysis of Multilineage Differentiation of Human Embryonic Stem Cells
Wei Xie,Matthew D. Schultz,Ryan Lister,Zhonggang Hou,Nisha Rajagopal,Pradipta R. Ray,John W. Whitaker,Shulan Tian,R. David Hawkins,Danny Leung,Hongbo Yang,Tao Wang,Ah Young Lee,Scott Swanson,Jiuchun Zhang,Jiuchun Zhang,Yun Zhu,Audrey Kim,Joseph R. Nery,Mark A. Urich,Samantha Kuan,Chia-An Yen,Sarit Klugman,Pengzhi Yu,Kran Suknuntha,Nicholas E. Propson,Huaming Chen,Lee Edsall,Ulrich Wagner,Yan Li,Zhen Ye,Ashwinikumar Kulkarni,Zhenyu Xuan,Wen Yu Chung,Neil C. Chi,Jessica Antosiewicz-Bourget,Igor I. Slukvin,Ron Stewart,Michael Q. Zhang,Michael Q. Zhang,Wei Wang,James A. Thomson,James A. Thomson,James A. Thomson,Joseph R. Ecker,Bing Ren,Bing Ren +46 more
TL;DR: It is found that promoters that are active in early developmental stages tend to be CG rich and mainly engage H3K27me3 upon silencing in nonexpressing lineages, while promoters for genes expressed preferentially at later stages are often CG poor and primarily employ DNA methylation upon repression.
Journal ArticleDOI
Human embryonic stem cell-derived CD34+ cells : efficient production in the coculture with OP9 stromal cells and analysis of lymphohematopoietic potential
TL;DR: Data indicate that CD34+ cells generated through hES/OP9 coculture display several features of definitive hematopoietic stem cells.