Q
Que-Minh Ngo
Researcher at Ludwig Institute for Cancer Research
Publications - 3
Citations - 1701
Que-Minh Ngo is an academic researcher from Ludwig Institute for Cancer Research. The author has contributed to research in topics: Epigenomics & DNA methylation. The author has an hindex of 3, co-authored 3 publications receiving 1350 citations. Previous affiliations of Que-Minh Ngo include University of California, San Diego.
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Journal ArticleDOI
Distinct epigenomic landscapes of pluripotent and lineage-committed human cells
R. David Hawkins,Gary C. Hon,Leonard Lee,Que-Minh Ngo,Ryan Lister,Mattia Pelizzola,Lee Edsall,Samantha Kuan,Ying Luu,Sarit Klugman,Jessica Antosiewicz-Bourget,Zhen Ye,Celso A. Espinoza,Saurabh Agarwahl,Li Shen,Victor Ruotti,Victor Ruotti,Wei Wang,Ron Stewart,Ron Stewart,James A. Thomson,Joseph R. Ecker,Bing Ren,Bing Ren +23 more
TL;DR: By comparing the chromatin-modification profiles and DNA methylomes in hESCs and primary fibroblasts, it is found that nearly one-third of the genome differs in chromatin structure.
Human DNA methylomes at base resolution show widespread epigenomic
Mattia Pelizzola,Robert H. Dowen,R. David Hawkins,Gary C. Hon,Julian Tonti-Filippini,Joseph R. Nery,Leonard K. Lee,Zhen Ye,Que-Minh Ngo,Lee Edsall,Jessica Antosiewicz-Bourget,Ronald M. Stewart,Victor Ruotti,A. Harvey Millar,James A. Thomson,Bing Ren,Joseph R. Ecker +16 more
TL;DR: The first genome-wide, single-base-resolution maps of methylated cytosine methylation in a mammalian genome are presented, from both human embryonic stem cells and fetal fibroblasts, along with comparative analysis of messenger RNA and small RNA components of the transcriptome, several histone modifications, and sites of DNA–protein interaction for several key regulatory factors.
Journal ArticleDOI
An assessment of histone-modification antibody quality
Thea A. Egelhofer,Aki Minoda,Aki Minoda,Sarit Klugman,Sarit Klugman,Kyungjoon Lee,P. Kolasinska-Zwierz,Artyom A. Alekseyenko,Ming Sin Cheung,Daniel S. Day,Sarah Gadel,Andrey A. Gorchakov,Tingting Gu,Peter V. Kharchenko,Samantha Kuan,Samantha Kuan,Isabel J. Latorre,Daniela Linder-Basso,Ying Luu,Ying Luu,Que-Minh Ngo,Que-Minh Ngo,Marc D. Perry,Andreas Rechtsteiner,Nicole C. Riddle,Yuri B. Schwartz,Gregory A. Shanower,A. Vielle,Julie Ahringer,Sarah C. R. Elgin,Mitzi I. Kuroda,Vincenzo Pirrotta,Bing Ren,Bing Ren,Susan Strome,Peter J. Park,Gary H. Karpen,Gary H. Karpen,R. David Hawkins,R. David Hawkins,Jason D. Lieb +40 more
TL;DR: The specificity and utility of histone-modification antibodies raised against 57 different histone modifications in Drosophila melanogaster, Caenorhabditis elegans and human cells are tested.