V
Victoria M. Perreau
Researcher at Florey Institute of Neuroscience and Mental Health
Publications - 49
Citations - 5319
Victoria M. Perreau is an academic researcher from Florey Institute of Neuroscience and Mental Health. The author has contributed to research in topics: Gene expression & Gene expression profiling. The author has an hindex of 28, co-authored 48 publications receiving 4855 citations. Previous affiliations of Victoria M. Perreau include University of California, Irvine & University of Kent.
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Journal ArticleDOI
Voluntary Exercise Decreases Amyloid Load in a Transgenic Model of Alzheimer's Disease
TL;DR: It is demonstrated that exercise is a simple behavioral intervention sufficient to inhibit the normal progression of AD-like neuropathology in the TgCRND8 mouse model.
Journal ArticleDOI
The IntAct molecular interaction database in 2010
Bruno Aranda,P. Achuthan,Yasmin Alam-Faruque,Irina M. Armean,Alan Bridge,C. Derow,M Feuermann,Avazeh T. Ghanbarian,Samuel Kerrien,Jyoti Khadake,J. Kerssemakers,C. Leroy,Michael P. Menden,Magali Michaut,Luisa Montecchi-Palazzi,S. N. Neuhauser,Sandra Orchard,Victoria M. Perreau,Bernd Roechert,K. van Eijk,Henning Hermjakob +20 more
TL;DR: In response to the growing data volume and user requests, IntAct now provides a two-tiered view of the interaction data, which allows the user to iteratively develop complex queries, exploiting the detailed annotation with hierarchical controlled vocabularies.
Journal ArticleDOI
Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20
Melanie Bahlo,David R. Booth,Simon A. Broadley,Matthew A. Brown,Matthew A. Brown,Simon J. Foote,Lyn R. Griffiths,Trevor J. Kilpatrick,Trevor J. Kilpatrick,Jeanette Lechner-Scott,Pablo Moscato,Victoria M. Perreau,Justin P. Rubio,Rodney J. Scott,Rodney J. Scott,Jim Stankovich,Graeme J. Stewart,Bruce V. Taylor,James S. Wiley,Glynnis Clarke,Mathew B Cox,Peter A. Csurhes,Patrick Danoy,Karen E. Drysdale,Judith Field,Judith M. Greer,Preethi Guru,Johanna Hadler,Brendan J. McMorran,Cathy J Jensen,Laura J. Johnson,Ruth McCallum,Marilyn E. Merriman,Tony R. Merriman,Karen Pryce,Lotfi Tajouri,Ella J Wilkins,Brian L. Browning,Sharon R. Browning,D. I. Perera,Simon Broadley,Helmut Butzkueven,Helmut Butzkueven,William M. Carroll,Caron Chapman,Allan G. Kermode,Mark Marriott,Deborah F. Mason,Robert Heard,Michael P. Pender,Michael P. Pender,Mark Slee,Niall Tubridy,Ernest Willoughby +53 more
TL;DR: To identify multiple sclerosis (MS) susceptibility loci, a genome-wide association study in 1,618 cases and used shared data for 3,413 controls and observed a statistical interaction between SNPs in EVI5-RPL5 and HLA-DR15.
Journal ArticleDOI
Extensive innate immune gene activation accompanies brain aging, increasing vulnerability to cognitive decline and neurodegeneration: a microarray study
David H. Cribbs,Nicole C. Berchtold,Victoria M. Perreau,Paul D. Coleman,Joseph G. Rogers,Andrea J. Tenner,Carl W. Cotman +6 more
TL;DR: The extent of innate immune gene upregulation in AD was modest relative to the robust response apparent in the aged brain, consistent with the emerging idea of a critical involvement of inflammation in the earliest stages, perhaps even in the preclinical stage, of AD.
Journal ArticleDOI
Axonal mRNA in uninjured and regenerating cortical mammalian axons.
Anne Marion Taylor,Nicole C. Berchtold,Victoria M. Perreau,Victoria M. Perreau,Christina H. Tu,Noo Li Jeon,Carl W. Cotman +6 more
TL;DR: The data demonstrate that CNS axons contain many mRNA species of diverse functions, and suggest that, like invertebrate and PNS axons, CNS axon synthesize proteins locally, maintaining a degree of autonomy from the cell body.